T-independent antigen
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  T-independent antigen

T-independent antigen

    An immunogen which induces antibody synthesis in the absence of lymphokines released by T cells; the antibodies are generally only of the IgM isotype.


A substance capable of inducing an immune response (as well as reacting with the products of an immune response). Compare with antigen.

An infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (eg, bacteria, viruses) or toxins. Antibodies, known generally as immunoglobulins, are made and secreted by B-lymphocytes in response to stimulation by antigens. Each specific antibody binds only to the specific antigen that stimulated its production.

Soluble substances secreted by lymphocytes, which have a variety of effects on lymphocytes and other cell types.

Proteins produced by white blood cells. They confer immunity.



Infection of the mucous membranes of the mouth by a fungus of the genus candida.

Sounds that are perceived in the absence of any external noise source which may take the form of buzzing, ringing, clicking, pulsations, and other noises. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of cochlear diseases; vestibulocochlear nerve diseases; intracranial hypertension; craniocerebral trauma; and other conditions.

A genus of parasitic flagellate protozoans distinguished by the presence of four anterior flagella, an undulating membrane, and a trailing flagellum.

Any of the infectious diseases of man and other animals caused by species of mycobacterium.

T-dependent antigen
An immunogen that is able to induce antibody synthesis only in the presence of lymphokines released by helper T cells.

T-independent antigen

The reciprocal of the last dilution of a titration giving a measurable effect; e.g. if the last dilution giving significant agglutination is 1:128, the titre is 128.

Diminished or absent capacity to make a specific response to an antigen, usually produced as a result of contact with that antigen under nonimmunizing conditions.

A nontoxic derivative of a toxin used as an immunogen for the induction of antibodies capable of cross-reacting with the toxin.

Tenuate is the brand name for diethylpropion. Diethylpropion is a sympathomimetic amine similar to an amphetamine, also known as an "anorectic" or an "anorexigenic" medication. Tenuate stimulates the central nervous system (nerves and brain)increasing the heart rate and blood pressure and decreasing the appetite. This drug is used as a short-term supplement to diet and exercise in the treatment of obesity and should only be taken with a medical prescription. Outside US it may be found under the name of Neobes.

Telangiectasia are dilated superficial blood vessels. This appearance may occur in rosacea, in certain systemic diseases like ataxia-telangiectasia, scleroderma or in some long-term therapy with topical fluorinated corticosteroids. Telangiectasia may also occur as a component of inherited disorders, including hereditary hemorrhagic telangiectasia.

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