Single-blind study
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  Single-blind study

Single-blind study

   One in which subjects do not know whether they are receiving the active drug or a placebo, but the investigator does know


A placebo is an inactive pill, liquid, or powder that has no treatment value. In clinical trials, experimental treatments are often compared with placebos to assess the treatment's effectiveness. In some studies, the participants in the control group will receive a placebo instead of an active drug or treatment. No sick participant receives a placebo if there is a known beneficial treatment.

A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at a trial site, the Investigator is the responsible leader of the team and may be called the Principal Investigator.


Singapore doctor
A doctor who, being or not a citizen of that country, has been admitted to practice medicine in Singapore.

Singapore doctors
All doctors near Singapore, Singapore. Doctors who can assist a patient in Singapore.

Singapore Gamma Knife Centre
The Singapore Gamma Knife Centre is a hospital in Singapore.

Singapore General Hospital
The Singapore General Hospital is a hospital in Singapore.

Singapore National Eye Centre
The Singapore National Eye Centre is a hospital in Singapore.

Singing River Hospital System
Singing River Hospital System is a hospital in Pascagoula, Mississippi (USA).

Singleton District Hospital
The Singleton District Hospital is a hospital in Singleton, New South Wales, Australia.

Singleton Hospital
The Singleton Hospital is a hospital in Swansea, Wales (Great Britain).

Singling-Larsen-Johanssen syndrome
Pain at the insertion of the patellar tendon to the patella. Occurs in adolescence and calcification may be seen here on X-ray.

Singulair is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): montelukast sodium.


Simian Virus 40, a monkey virus that contaminated the polio vaccine administered to 98 million Americans from 1955 to 1963, and has been associated with a number of rare human cancers. One controversial theory links SV40 to mesothelioma.

relative freedom from harm; in clinical trials, this refers to an absence of harmful side effects resulting from use of the product and may be assessed by laboratory testing of biological samples, special tests and procedures, psychiatric evaluation, and/or physical examination of subjects.

Safety and tolerability
The safety of a medical product concerns the medical risk to the subject, usually assessed in a clinical trial by laboratory tests (including clinical chemistry and haematology), vital signs, clinical adverse events (diseases, signs and symptoms), and other special safety, tests (for example, ECGs opthamology). The tolerability of the medical product represents the degree to which overt adverse effects can be tolerated by the subject

Serious adverse drug reaction (SADR)
A serious adverse event (SAE) which is possibly an adverse drug reaction (ADR)

Serious adverse event (SAE)
Any untoward medical occurrence that results in death, is life threatening, requires inpatient hospitalisation or prolongation of existing hospitalisation, results in persistent or significant disability/incapacity, or is a congenital anomaly/birth defect. See adverse event (AE)

Single-blind study

Source data
All information in original records and certified copies of original records of clinical findings, observations, or other activities in a clinical trial necessary for the reconstruction and evaluation of the trial. Source data are contained in source documents (original records or certified copies)

An individual, company, institution, or organisation which takes responsibility for the initiation, management, and/or financing of a clinical trial

Standard deviation (statistics)
Indicator of the relative variability of a variable around its mean; the square root of the variance

Standard operating procedures (S0Ps)
Detailed, written instructions to achieve uniformity of the performance of a specific function

Statistical analysis plan
A document that contains a more technical and detailed elaboration of the principal features of the analysis described in the protocol, and includes detailed procedures for executing the statistical analysis of the primary and secondary, variables and other data.

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