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   The most frequently occurring value in a data set.



see blinding/masking.

See pairing.

The sum of the values of all observations or data points divided by the number of observations, an arithmetical average.

Massive randomised clinical trials that test the advantages of marginally effective experimental drugs by enrolling 10,000 or more subjects.

A statistical process for pooling data from many clinical trials to glean a clear answer.


The act of overseeing the progress of a clinical trial, and of ensuring that it is conducted, recorded, and reported in accordance with the protocol, standard operating procedures (S0Ps), good clinical practice (GCP), and the applicable regulatory requirement(s).

Monitoring committee
See independent data-monitoring committee.

Monitoring report
A written report from the monitor to the investigators after each site visit and/or other trial-related communication according to the relevant SOPS.

Statistics on deaths within a population based on official death certificates, usually showing numbers of deaths by age, sex and cause.

Multicentre trial
A clinical trial conducted according to a single protocol but at more than one site, and therefore, carried out by more than one investigator.

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