Intron
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  Intron



Intron

    A segment of DNA that does not code for protein; the intervening sequence of nucleotides between coding sequences or exons.

RELATED TERMS
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Code
The genetic code is the correspondence between the triplet of bases in DNA with the amino acids.

Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.

Nucleotides
The components of DNA, consisting of phosphate, a sugar derivative and one of the following bases: adenine, cytosine, guanine, or thymine. They are represented by their initial letters in a nucleotide sequence.

Exons
The parts of a genetic transcript remaining after the INTRONS are removed and which are spliced together to become a messenger or structural RNA.



SIMILAR TERMS
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Intra-aortic Balloon Pump Assist Device
The intra-aortic balloon pump is a machine that can help the pumping function of the heart. It is usually inserted through an artery in the groin area and threaded backwards into the descending thoracic aorta in the chest. In this location the balloon inflates and deflates in synchrony with the heart in order to aid the blood pumping function of the heart in patients with cardiac disease.

Intra-arterial
Injection into an artery (that may supply a tumor).

Intracardiac Tumor
An Intracardiac Tumor can be any tumor of the heart, either malignant or benign. The most common tumor of the heart is a benign atrial myxoma.

Intracellular
Within cells.

Intracerebral
Located within the cerebral hemispheres (cerebrum). See extracerebral.

Intracerebral haemorrhage
Haemorrhage within the brain.

Intracranial
Within the skull.

Intracutan test
Intracutan tests are used to diagnose allergies. A small amount of allergen extract is injected under the skin on your arm. If the area becomes itchy, reddish and swelling you may have an allergy.

Intracytoplasmic sperm injection
An assisted reproductive method in which a sperm is injected directly into an unfertilized egg with a microscopic needle; this procedure is used in cases of severe male factor infertility.

Intradermal
Within the skin.

Intradural
Beneath the dura mater.

Intralipid 10 per cent
Intralipid 10 per cent is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): soybean oil.

Intralipid 20 per cent
Intralipid 20 per cent is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): soybean oil.

Intralipid 30 per cent
Intralipid 30 per cent is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): soybean oil.

Intramuscular
Intra (within) muscular (muscle) techniques are ways to put medication into the body, by injecting it into a muscle. This is designed for drugs that need to be absorbed slowly. A classic example is a tetanus shot.

Intramuscular Injection
Putting a fluid into a muscle with a needle and syringe.

Intraoral camera
A smal video camera used to view and magnify oral conditions; images may be printed.

Intrapartal care
Care for a pregnant woman through labor.

Intraperitoneally
Inserting chemotherapy drugs directly into the abdominal cavity. Intraoperative photodynamic therapy is a new treatment that uses special drugs and light to kill cancer cells. Its use in the early states of mesothelioma in the chest is being studied. Judgement - an official court order deciding the rights or claims of the parties in a legal proceeding.

Intrapleurally
Inserting chemotherapy drugs directly into the chest cavity.

Intrarater reliability
The property of yielding equivalent results when used by the same rater on different occasions.

Intrathecal
Injection into the sub-arachnoid space of the meninges. Usually done by lumbar puncture.

Intratumoral
Injection into a tumor (usually performed during surgery).

Intrauterine
Within the womb.

Intrauterine device
A small engineered piece of plastic or metal placed in a woman's uterus to prevent fertilization.

Intrauterine growth retardation
Slow growth of a fetus in the womb possibly resulting in a low birth weight baby.

Intrauterine insemination
Treatment for infertility in which semen is introduced into the uterus via a slim tube inserted through the vagina.

Intravascular
Inside a blood vessel.

Intravascular echocardiography
Echocardiography and cardiac catheterization.

Intravascular ultrasound (IVUS)
An invasive procedure, performed along with cardiac catheterization; a miniature sound probe (transducer) on the tip of a coronary catheter is threaded through the coronary arteries and, using high-frequency sound waves, produces detailed images of the interior walls of the arteries.

Intravenous
Introducing a fluid into the bloodstream through a vein (usually in the patient's forearm).

Intravenous (IV)
Delivery of drugs, fluids or food directly into a vein.

Intravenous Injection
Putting a fluid into a vein with a needle and syringe.

Intraventricular
Injection into a ventricle.

Intraventricular hemorrhage
Bleeding into the ventricles or the brain, common in premature infants.

Intrinsic asthma
Asthma that has no apparent external cause.

Introceptive
Pertaining to a sensory organ that registers information from within the body.

Intromission
The insertion of one part into another; in sexual intercourse, the insertion of the penis into the vagina.

Intron a
Intron a is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): interferon alfa-2b.

Intropin
Intropin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): dopamine hydrochloride.

Introspection
Self-observation; examination of one's feelings, often as a result of psychotherapy.

Introversion
Preoccupation with oneself and accompanying reduction of interest in the outside world. Contrast to extraversion.



PREVIOUS AND NEXT TERMS
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Immune response (Ir) gene
A gene controlling an immune response to a particular antigen; most genes of this type are in the MHC (major histocompatibility complex), and the term is rarely used to describe other types of Ir genes outside the MHC.

Immunogen
A substance capable of inducing an immune response (as well as reacting with the products of an immune response). Compare with antigen.

Immunoglobulin (Ig)
A general term for all antibody molecules. Each Ig unit is made up of two heavy chains and two light chains and has two antigen- binding sites.

Interferon
A group of proteins having antiviral activity and capable of enhancing and modifying the immune response.

Internal image
A spatial configuration of the combining site of an anti-idiotype antibody which resembles the epitope to which the idiotype is directed.

Intron

Isograft
A tissue transplanted between two genetically identical individuals.

Isohemagglutinins
Antibodies to major red blood cell antigens present normally as a result of inapparent immunization by cross-reactive antigens in bacteria, food, etc.

Isotypes
Classes of antibody that differ in the constant region of their heavy chain (Fc portion); distinguishable also on the basis of reaction with antisera raised in another species. These differences also result in different biological activities of the antibodies.

Isotype switch
The shift of a B cell or its progeny from the secretion of antibody of one isotype or class of antibody with the same V regions but a different heavy- chain constant region and, hence, a different isotype (class switch).

IAG
Idiopathic adolescent gynecomastia, occurring in males The unilateral or bilateral abnormal development of breast tissue in adolescent males. Hormone therapy or breast reduction surgery is sometimes indicated.

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