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    Idiopathic adolescent gynecomastia, occurring in males The unilateral or bilateral abnormal development of breast tissue in adolescent males. Hormone therapy or breast reduction surgery is sometimes indicated.


Of unexplained origin, as in the development of a symptom or syndrome that is apparently spontaneously generated.

The period of life beginning with the appearance of secondary sex characteristics and terminating with the cessation of somatic growth. The years usually referred to as adolescence lie between 13 and 18 years of age.

The development of breasts on a male, spontaneously or as a result of hormonal treatment.

Affecting only one side.

Affecting both sides.

Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).

The process of growth and differentiation.

The breast refers to the front of the chest or, more specifically, to the mammary gland. The mammary gland is a milk producing gland. It is composed largely of fat. Within the mammary gland is a complex network of branching ducts. These ducts exit from sac-like structures called lobules, which can produce milk in females. The ducts exit the breast at the nipple.

Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.

A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions.

Treating diseases or other medical conditions by operating on a patient to remove or repair parts of the body.



A segment of DNA that does not code for protein; the intervening sequence of nucleotides between coding sequences or exons.

A tissue transplanted between two genetically identical individuals.

Antibodies to major red blood cell antigens present normally as a result of inapparent immunization by cross-reactive antigens in bacteria, food, etc.

Classes of antibody that differ in the constant region of their heavy chain (Fc portion); distinguishable also on the basis of reaction with antisera raised in another species. These differences also result in different biological activities of the antibodies.

Isotype switch
The shift of a B cell or its progeny from the secretion of antibody of one isotype or class of antibody with the same V regions but a different heavy- chain constant region and, hence, a different isotype (class switch).


Generated or induced by the physician; pertaining to physical or mental aliments or disease due to the actions of the physician, as in iatrogenic disease, the result of exposure to pathogens, toxins or injurious treatment or procedures by the physician, or from alarming or traumatizing diagnosis.

Interstitial cell stimulating hormone; LH (luteninizing hormone).

Pertaining to the period when an epileptic seizure or seizure-like attack takes place.

In mental life, the collective representation of thoughts and ideas presently recognized, recalled from memory, or projected into the future, singly or in combination.

The process of becoming like someone as a sequel to assimilating or copying that person's activities, behavior, and reactions. The term is applied especially to the differentiation of G-I/R (gender identity/role).

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