Granulocyte
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  Granulocyte



Granulocyte

   Leukocytes with abundant granules in the cytoplasm. They are divided into three groups: NEUTROPHILS; EOSINOPHILS; and BASOPHILS.

RELATED TERMS
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Leukocytes
White blood cells, the blood cells responsible for fighting infection.

Cytoplasm
The living matter within a cell (excluding the nucleus) that is responsible for the function of the cell (for example, protein synthesis).

EOSINOPHILS
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.



SIMILAR TERMS
--------------------------------------

Grana
Membranous cisternae of the chloroplast containing photosynthetic pigments, reaction centers, and the electron-transport chain. Each thylakoid consists of a flattened sac of membrane enclosing a narrow intra-thylakoid space (Lackie and Dow, Dictionary of Cell Biology, 2nd ed). Individual thylakoids are interconnected and tend to stack to form aggregates called grana. They are found in cyanobacteria and all plants.

Granada doctors
All doctors near Granada, Spain. Doctors who can assist a patient in Granada.

Granada Hills Community Hospital
The Granada Hills Community Hospital is a hospital in Los Angeles, California, United States.

Granadilla
A plant genus of the family Passifloraceae, order Violales, subclass Dilleniidae, class Magnoliopsida. They are vines with ornamental flowers and edible fruit.

Grand Cayman doctor
A doctor who, being or not a citizen of that country, has been admitted to practice medicine in Grand Cayman.

Grand mal
A seizure characterized by loss of consciousness with general tonic/clonic (musculature contractions and relaxation in rapid succession also with tension) movements.

Grand Mal Convulsion
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Grand Mal Convulsions
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Grand Mal Epilepsy
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Grand mal seizure
An epileptic seizure with convulsing and unconsciousness.

Grand Mal Seizure Disorder
A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Grand Mal Status Epilepticus
A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Grand Prairie doctors
All doctors near Grand Prairie, the United States of America. Doctors who can assist a patient in Grand Prairie.

Grand Rapids doctors
All doctors near Grand Rapids, the United States of America. Doctors who can assist a patient in Grand Rapids.

Grand Strand Regional Medical Center
Grand Strand Regional Medical Center is a hospital in Myrtle Beach, South Carolina (USA).

Grand Turk doctors
All doctors near Grand Turk, the Turks and Caicos Islands. Doctors who can assist a patient in Grand Turk.

Grand View Hospital
Grand View Hospital is a hospital in Sellersville, Pennsylvania (USA).

Grand View Medical Center
Grand View Medical Center is a hospital in Jasper, Tennessee (USA).

Grandiose delusion
A delusion of inflated worth, power, knowledge, identity, or special relationship to a deity or famous person.

Grandiosity
An inflated appraisal of one's worth, power, knowledge, importance, or identity. When extreme, grandiosity may be of delusional proportions.

Grandview Health Homes Inc
The Grandview Health Homes Inc is a hospital in Danville, Pennsylvania, United States.

Grandview Surgery and Laser Center
The Grandview Surgery and Laser Center is a hospital in Camp Hill, Pennsylvania, United States.

Granisetron
Granisetron is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): granisetron hydrochloride.

Granisetron Hydrochloride
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.

Granisetron Monohydrochloride
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.

Granosan
A highly toxic compound used as a fungicide for treating seeds.

Grant
All organized methods of funding.

Grant Hospital
Grant Hospital is a hospital in Columbus, Ohio (USA).

Grant, Educational
Financial support for training including both student stipends and loans and training grants to institutions.

Grant, Peer Review
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.

Grantham Hospital
The Grantham Hospital is a hospital in Hong Kong.

Grants
All organized methods of funding.

Grants and Subsidies, Educational
Financial support for training including both student stipends and loans and training grants to institutions.

Grants and Subsidies, Government
Federal, state, or local government organized methods of financial assistance.

Grants and Subsidies, Health Planning
Financial resources provided for activities related to health planning and development.

Grants and Subsidies, Research
Financial support of research activities.

Grants Peer Review
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.

Grants Peer Reviews
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.

Grants, Educational
Financial support for training including both student stipends and loans and training grants to institutions.

Grants, Peer Review
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.

Granular Cell Adenocarcinoma
A malignant epithelial tumor with a glandular organization.

Granular Cell Adenocarcinomas
A malignant epithelial tumor with a glandular organization.

Granular Cell Carcinoma
A malignant epithelial tumor with a glandular organization.

Granular Cell Carcinomas
A malignant epithelial tumor with a glandular organization.

Granular Cell Myoblastoma
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.

Granular Cell Myoblastomas
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.

Granular Cell Tumor
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.

Granular Cell Tumors
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.

Granular Dystrophies, Corneal
Bilateral hereditary disorders of the cornea, usually autosomal dominant, which may be present at birth but more frequently develop during adolescence and progress slowly throughout life. Central macular dystrophy is transmitted as an autosomal recessive defect.

Granular Dystrophy, Corneal
Bilateral hereditary disorders of the cornea, usually autosomal dominant, which may be present at birth but more frequently develop during adolescence and progress slowly throughout life. Central macular dystrophy is transmitted as an autosomal recessive defect.

Granular Endoplasmic Reticulum
A type of endoplasmic reticulum (ER) where polyribosomes are present on the cytoplasmic surfaces of the ER membranes. This form of ER is prominent in cells specialized for protein secretion and its principal function is to segregate proteins destined for export or intracellular utilization.

Granulation Tissue
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.

Granulation Tissues
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.

Granule Bound Starch Synthase
An enzyme that catalyzes the transfer of glucose from ADPglucose to glucose-containing polysaccharides in 1,4-alpha-linkages. EC 2.4.1.21.

Granule, Chromaffin
Granules in the adrenal glands and various other organs, which are concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.

Granule, Cytoplasmic
Condensed areas of cellular material that may be bounded by a membrane.

Granule, Nissl
Subcellular structures found in nerve cell bodies and DENDRITES. They consist of granular endoplasmic reticulum (ENDOPLASMIC RETICULUM, ROUGH) and RIBOSOMES.

Granule, Secretory
Vesicles derived from the GOLGI APPARATUS containing material to be released at the cell surface.

Granule-Bound Starch Synthase
An enzyme that catalyzes the transfer of glucose from ADPglucose to glucose-containing polysaccharides in 1,4-alpha-linkages. EC 2.4.1.21.

Granules, Chromaffin
Granules in the adrenal glands and various other organs, which are concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.

Granules, Cytoplasmic
Condensed areas of cellular material that may be bounded by a membrane.

Granules, Nissl
Subcellular structures found in nerve cell bodies and DENDRITES. They consist of granular endoplasmic reticulum (ENDOPLASMIC RETICULUM, ROUGH) and RIBOSOMES.

Granules, Secretory
Vesicles derived from the GOLGI APPARATUS containing material to be released at the cell surface.

Granulin Matrix Proteins
Proteins associated with the inner surface of the lipid bilayer of the viral envelope. These proteins have been implicated in control of viral transcription and may possibly serve as the ""glue"" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell.

Granulocyte Chemotactic Peptide Interleukin 8
A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. IL-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4.

Granulocyte Chemotactic Peptide-Interleukin-8
A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. IL-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4.

Granulocyte Colony Stimulating Factor, Recombinant
Granulocyte colony stimulating factors prepared by recombinant DNA technology.

Granulocyte Colony-Stimulating Factor
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

Granulocyte Elastase
An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with greater specificity for Ala. EC 3.4.21.37.

Granulocyte Macrophage Colony Stimulating Factor
An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

Granulocyte Macrophage Colony-Stimulating Factors, Recombinant
Granulocyte-macrophage colony-stimulating factors prepared by recombinant DNA technology.

Granulocyte-Macrophage Colony-Stimulating Factor
An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

Granulocytes
Leukocytes with abundant granules in the cytoplasm. They are divided into three groups: NEUTROPHILS; EOSINOPHILS; and BASOPHILS.

Granulocytic Leukemia
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors in the bone marrow and other sites.

Granulocytic Leukemias
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors in the bone marrow and other sites.

Granulocytic Sarcoma
An extramedullary tumor of immature myeloid cells. Granulocytic sarcoma usually occurs with or follows the onset of acute myeloid leukemia (LEUKEMIA, MYELOCYTIC, ACUTE).

Granulocytic Sarcomas
An extramedullary tumor of immature myeloid cells. Granulocytic sarcoma usually occurs with or follows the onset of acute myeloid leukemia (LEUKEMIA, MYELOCYTIC, ACUTE).

Granulocytopenia
Less than the normal number of granular leukocytes in the blood.

Granulocytopenias
A decrease in the number of GRANULOCYTES (BASOPHILS, EOSINOPHILS, and NEUTROPHILS).

Granuloma
A mass of red, irritated tissue in the GI tract found in Crohn's disease.

Granuloma Annulare
Benign granulomatous disease of unknown etiology characterized by a ring of localized or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures.

Granuloma Gangraenescens
A non-neoplastic disease of unknown etiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures.

Granuloma Inguinale
Anogenital ulcers caused by Calymmatobacterium granulomatis as distinguished from lymphogranuloma inguinale (see LYMPHOGRANULOMA VENEREUM) caused by CHLAMYDIA TRACHOMATIS. Diagnosis is made by demonstration of typical intracellular Donovan bodies in crushed-tissue smears.

Granuloma Pyogenicum
A disorder of the skin, the oral mucosa, and the gingiva, that usually presents as a solitary polypoid capillary hemangioma often resulting from trauma. It is manifested as an inflammatory response with similar characteristics to those of a granuloma.

Granuloma Telangiecticum
A disorder of the skin, the oral mucosa, and the gingiva, that usually presents as a solitary polypoid capillary hemangioma often resulting from trauma. It is manifested as an inflammatory response with similar characteristics to those of a granuloma.

Granuloma Venereum
Anogenital ulcers caused by Calymmatobacterium granulomatis as distinguished from lymphogranuloma inguinale (see LYMPHOGRANULOMA VENEREUM) caused by CHLAMYDIA TRACHOMATIS. Diagnosis is made by demonstration of typical intracellular Donovan bodies in crushed-tissue smears.

Granuloma, Dental
Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.

Granuloma, Eosinophilic
The most benign clinical form of Langerhans-cell histiocytosis (HISTIOCYTOSIS, LANGERHANS-CELL), which involves localized nodular lesions of the gastric mucosa, small intestine, bones, lungs, or skin, with infiltration by eosinophils. The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell.

Granuloma, Foreign Body
Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.

Granuloma, Foreign-Body
Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.

Granuloma, Giant Cell
A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.

Granuloma, Giant Cell Reparative
A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.

Granuloma, Hodgkin
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (REED-STERNBERG CELLS) of unknown origin.

Granuloma, Hodgkins
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (REED-STERNBERG CELLS) of unknown origin.

Granuloma, Laryngeal
A polypoid granulomatous projection into the lumen of the larynx.

Granuloma, Lethal Midline
A non-neoplastic disease of unknown etiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures.

Granuloma, Malignant
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (REED-STERNBERG CELLS) of unknown origin.

Granuloma, Periapical
Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.

Granuloma, Plasma Cell
A slow-growing benign pseudotumor in which plasma cells greatly outnumber the inflammatory cells.

Granuloma, Plasma Cell, Orbital
A chronic neoplasm-like inflammatory reaction, usually affecting the orbital tissues of both eyes, also known as orbital myositis.

Granuloma, Plasma Cell, Pulmonary
A pseudotumor of the lung composed of inflammatory cells and showing complete maturity of fibroblastic components with a striking lack of mitosis. It is also called postinflammatory pseudotumor and pseudoneoplastic pneumonitis. (Surg Gynecol Obstet 1983 Jan;156(1):89-96)

Granuloma, Pseudopyogenic
Solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells.

Granuloma, Pyogenic
A disorder of the skin, the oral mucosa, and the gingiva, that usually presents as a solitary polypoid capillary hemangioma often resulting from trauma. It is manifested as an inflammatory response with similar characteristics to those of a granuloma.

Granuloma, Respiratory Tract
Granulomatous disorders affecting one or more sites in the respiratory tract.

Granulomas
A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Granulomas, Dental
Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.

Granulomas, Eosinophilic
The most benign clinical form of Langerhans-cell histiocytosis (HISTIOCYTOSIS, LANGERHANS-CELL), which involves localized nodular lesions of the gastric mucosa, small intestine, bones, lungs, or skin, with infiltration by eosinophils. The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell.

Granulomas, Foreign-Body
Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.

Granulomas, Giant Cell
A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.

Granulomas, Laryngeal
A polypoid granulomatous projection into the lumen of the larynx.

Granulomas, Lethal Midline
A non-neoplastic disease of unknown etiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures.

Granulomas, Periapical
Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment.

Granulomas, Plasma Cell
A slow-growing benign pseudotumor in which plasma cells greatly outnumber the inflammatory cells.

Granulomas, Pseudopyogenic
Solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells.

Granulomas, Respiratory Tract
Granulomatous disorders affecting one or more sites in the respiratory tract.

Granulomatoses, Lymphomatoid
An angiocentric and angiodestructive lymphoreticular proliferative disorder primarily involving the lungs. Histologically it simulates malignant lymphoma and in some cases may progress to lymphoma.

Granulomatosis, Langerhans-Cell
Group of disorders of histiocyte proliferation which includes LETTERER-SIWE DISEASE; HAND-SCHUELLER-CHRISTIAN SYNDROME; and EOSINOPHILIC GRANULOMA. Langerhans cells are components of the lesions.

Granulomatosis, Lymphomatoid
An angiocentric and angiodestructive lymphoreticular proliferative disorder primarily involving the lungs. Histologically it simulates malignant lymphoma and in some cases may progress to lymphoma.

Granulomatosis, Wegener
A multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen. (Dorland, 27th ed)

Granulomatosis, Wegeners
A multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen. (Dorland, 27th ed)

Granulomatous
Composed of granulomas.

Granulomatous Angiitides, Allergic
Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.

Granulomatous Angiitis, Allergic
Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.

Granulomatous Cheilitis
An idiopathic syndrome characterized by one or more of the following; recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue (lingua plicata). The onset is usually in childhood and relapses are common. Cheilitis granulomatosa is a monosymptomatic variant of this condition. (Dermatol Clin 1996 Apr;14(2):371-9; Magalini & Magalini, Dictionary of Medical Syndromes, 4th ed, p531)

Granulomatous Cheilitis, Miescher-Melkersson-Rosenthal
An idiopathic syndrome characterized by one or more of the following; recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue (lingua plicata). The onset is usually in childhood and relapses are common. Cheilitis granulomatosa is a monosymptomatic variant of this condition. (Dermatol Clin 1996 Apr;14(2):371-9; Magalini & Magalini, Dictionary of Medical Syndromes, 4th ed, p531)

Granulomatous colitis
Another name for Crohn's disease of the colon.

Granulomatous Disease, Chronic
A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.

Granulomatous Diseases, Chronic
A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.

Granulomatous enteritis
Another name for Crohn's disease of the small intestine.

Granulomatous Slack Skin
A group of lymphomas exhibiting clonal expansion of malignant T-lymphocytes arrested at varying stages of differentiation as well as malignant infiltration of the skin. MYCOSIS FUNGOIDES and SEZARY SYNDROME are the best characterized of these disorders.

Granulomous Cerebral Cryptococcoses
Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)

Granulomous Cerebral Cryptococcosis
Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)

Granulosa Cell
Cells of the membrana granulosa lining the vesicular ovarian follicle which become luteal cells after ovulation.

Granulosa Cell Tumor
An ovarian tumor originating in the cells of the primordial membrana granulosa of the graafian follicle. It may be associated with excessive production of estrogen (ESTROGENS).

Granulosa Cell Tumors
An ovarian tumor originating in the cells of the primordial membrana granulosa of the graafian follicle. It may be associated with excessive production of estrogen (ESTROGENS).

Granulosa Cells
Cells of the membrana granulosa lining the vesicular ovarian follicle which become luteal cells after ovulation.

Granulosis Virus
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by ovicylindrical occlusion bodies. The type species is Cydia pomonella granulovirus.

Granulosis Viruses
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by ovicylindrical occlusion bodies. The type species is Cydia pomonella granulovirus.

Granulovirus
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by ovicylindrical occlusion bodies. The type species is Cydia pomonella granulovirus.

Granulovirus, Cydia pomonella
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by ovicylindrical occlusion bodies. The type species is Cydia pomonella granulovirus.

Granuloviruses, Cydia pomonella
A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by ovicylindrical occlusion bodies. The type species is Cydia pomonella granulovirus.

Granville Medical Center
The Granville Medical Center is a hospital in Oxford, North Carolina, United States.



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Granadilla
A plant genus of the family Passifloraceae, order Violales, subclass Dilleniidae, class Magnoliopsida. They are vines with ornamental flowers and edible fruit.

Granulation Tissue
A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.

Granular Cell Tumor
Unusual tumor affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma.

Granulocyte Colony-Stimulating Factor
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

Granulocyte Colony Stimulating Factor, Recombinant
Granulocyte colony stimulating factors prepared by recombinant DNA technology.

Granulocyte

Granulin Matrix Proteins
Proteins associated with the inner surface of the lipid bilayer of the viral envelope. These proteins have been implicated in control of viral transcription and may possibly serve as the ""glue"" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell.

Granules, Nissl
Subcellular structures found in nerve cell bodies and DENDRITES. They consist of granular endoplasmic reticulum (ENDOPLASMIC RETICULUM, ROUGH) and RIBOSOMES.

Granules, Chromaffin
Granules in the adrenal glands and various other organs, which are concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.

Granuloma Gangraenescens
A non-neoplastic disease of unknown etiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures.

Granuloma Annulare
Benign granulomatous disease of unknown etiology characterized by a ring of localized or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures.

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