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  GenBank



GenBank

   DATABASES containing information about NUCLEIC ACIDS such as BASE SEQUENCE; SNPS (POLYMORPHISM, SINGLE NUCLEOTIDE); NUCLEIC ACID CONFORMATION; and other properties. Information about the DNA fragments kept in a GENE LIBRARY or GENOMIC LIBRARY is often maintained in DNA databases.

RELATED TERMS
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DATABASES
Organized collections of computer records, standardized in format and content, that are stored in any of a variety of computer-readable modes. They are the basic sets of data from which computer-readable files are created. (from ALA Glossary of Library and Information Science, 1983)

BASE
A chemical compound that either donates hydroxide ions or absorbs hydrogen ions when dissolved in water. Bases and acids are referred to as opposites because the effect of an acid is to increase the hydronium ion concentration in water, whereas bases reduce this concentration. Arrhenius bases are water-soluble and always have a pH greater than 7 in solution.

GENE
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.

GENOMIC
Pertaining to the genome, all of the genetic information possessed by any organism.

Databases
Organized collections of computer records, standardized in format and content, that are stored in any of a variety of computer-readable modes. They are the basic sets of data from which computer-readable files are created. (from ALA Glossary of Library and Information Science, 1983)



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Gender Relations
The reciprocal interaction of two or more persons.

Gender Relation
The reciprocal interaction of two or more persons.

Gender Issues
The reciprocal interaction of two or more persons.

Gender Issue
The reciprocal interaction of two or more persons.

Gender Bias
A preconceived judgment made without adequate evidence and not easily alterable by presentation of contrary evidence.

GenBank

Gemiton
An alpha-2 adrenergic agonist that crosses the blood-brain barrier. Clonidine acts centrally by reducing sympathetic tone, resulting in a fall in diastolic and systolic blood pressure and a reduction in heart rate. It also acts peripherally, and this peripheral activity may be responsible for the transient increase in blood pressure seen during rapid intravenous administration. (From Martindale, the Extra Pharmacopoeia, 30th ed, p350)

Gemistocytic Astrocytomas
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Gene Dosages
The number of copies of a given gene present in a cell or nucleus. An increase in gene dosage can result in the formation of higher levels of gene product, provided that the gene is not subject to autogenous regulation.

Gene Dosage
The number of copies of a given gene present in a cell or nucleus. An increase in gene dosage can result in the formation of higher levels of gene product, provided that the gene is not subject to autogenous regulation.

Gene Deletions
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.

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