Epicanthal fold
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  Epicanthal fold

Epicanthal fold

   A fold of skin that comes down across the inner angle (canthus) of the eye. The epicanthal fold is more common in children with Down syndrome and other birth defects than normal children and so is of value in diagnosis. Although some dictionaries state that this eye fold is found in peoples of Asian origin, this is not true. The normal Asian eyefold is continuous with the lower edge of the upper eyelid and actually appears distinctly different than a true epicanthal fold.


Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous.

A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection.

The determination of the presence of a specific disease or infection, usually accomplished by evaluating clinical symptoms and laboratory tests.

The lid or cover of the eye, a movable fold of skin and muscle that can be closed over the eyeball or opened at will. Each eye has an upper and a lower lid. An eyelid is also called a palpebra.


Epicapsular stars
Remnants left on the eye of the hyaloid canal, from development in the womb.

The membrane that covers the outside of the heart.

A antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.

Common to both sexes; neither one nor the other.

A chlorinated epoxy compound used as an industrial solvent. It is a strong skin irritant and carcinogen.

A chlorinated epoxy compound used as an industrial solvent. It is a strong skin irritant and carcinogen.

Epichlorohydrin, (+-)-Isomer
A chlorinated epoxy compound used as an industrial solvent. It is a strong skin irritant and carcinogen.

Epichlorohydrin, (S)-Isomer
A chlorinated epoxy compound used as an industrial solvent. It is a strong skin irritant and carcinogen.

The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

Epicondylitides, Lateral Humeral
A condition characterized by pain in or near the lateral humeral epicondyle or in the forearm extensor muscle mass as a result of unusual strain. It occurs in tennis players as well as housewives, artisans, and violinists.

Enthesopathy at humeral epicondyle. May be medial (golfer's elbow) or lateral (tennis elbow).

Epicondylitis, Lateral Humeral
A condition characterized by pain in or near the lateral humeral epicondyle or in the forearm extensor muscle mass as a result of unusual strain. It occurs in tennis players as well as housewives, artisans, and violinists.

Epicort is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

The main glucocorticoid secreted by the adrenal cortex. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.


The gene for familial eosinophilia. EOS has been mapped to chromosome region 5q31-33 containing the cytokine gene cluster which includes the genes for interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte colony-stimulating factor (G-CSF), and all of which are thought play roles in the development, proliferation, and activation of eosinophils.

An abnormally high number of eosinophils in the blood. Normally, eosinophils constitute 1 to 3% of the peripheral blood leukocytes, at a count of 350 to 650 per cubic millimeter. Eosinophilia can be categorized as mild (less than 1500 eosinophils per cubic millimeter), moderate (1500 to 5000 per cubic millimeter), or severe (more than 5000 per cubic millimeter).

Eosinophilic meningitis
Meningitis with a high percentage of eosinophils (a type of white blood cell) in the cerebrospinal fluid (CSF). The usual cause is the parasite Angiostrongylus cantonensis, also known as the rat lungworm. People become infected with this parasite by ingesting its larvae in raw or insufficiently cooked snails, slugs, freshwater prawns, frogs, or fish. Infection may also occur by consumption of fresh produce such as contaminated lettuce. When the larvae are ingested, they penetrate the intestinal tract, go into blood vessels, and eventually reach the meninges (the covering of the brain and spinal cord). The larvae usually die there shortly thereafter. An eosinophilic reaction develops in response to the dying larvae. It is manifested by an outpouring of eosinophils in the CSF.

The plural of ephelis, a type of freckle. Ephelis and ephelides are among the many medical terms that are rarely, if ever, encountered outside of medicine.

A form of freckle. A flat red or light-brown spot on the skin that typically appears during the sunny months and fades in the winter. They are most often found in people with light complexions and in some families, they are an hereditary (genetic) trait. The regular use of sunscreen during times of sun exposure helps to suppress the appearance of the ephelis-type freckle.

Epicanthal fold

The occurrence of more cases of a disease than would be expected in a community or region during a given time period. A sudden severe outbreak of a disease such as SARS.

Epidemic hemorrhagic fever
A number of diseases characterized by an abrupt onset of high fever and chills, headache, cold and cough, and pain in the muscles, joints and abdomen with nausea and vomiting followed by bleeding into the kidney and elsewhere. Known also as hemorrhagic fever with renal syndrome. Many arboviruses (including those in the families Togaviridae, Flaviviridae, Filoviridae, and Bunyaviridae) and the Hantaviruses, spread by rodents or biting insects, can cause epidemic hemorrhagic fever. The Ebola virus is a notorious cause of epidemic hemorrhagic fever.

Epidemic myalgia
Also known as Bornholm disease, this is a temporary illness that is a result of virus infection. The disease features fever and intense abdominal and chest pains with headache. The chest pain is typically worsened by breathing or coughing. The illness usually lasts from 3 to 14 days. The most common virus causing Bornholm disease is an enterovirus called Coxsackie B. Bornholm disease is also called pleurodynia (because of inflammation of the lining tissue of the lungs).

A person engaged in epidemiology (not confined to epidemics).

Epidemiology, classical
The study of populations in order to determine the frequency and distribution of disease and measure risks.

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