Eosinophilic fasciitis
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  Eosinophilic fasciitis



Eosinophilic fasciitis

    A scleroderma-like condition in which there is skin thickening and tethering with oedema along with thickening of the sub-epidermal fascia and infiltration with eosinophils. (Shulman's syndrome)

RELATED TERMS
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Condition
The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

Fascia
Tough membrane that encloses muscles and other organs.

Infiltration
Local anesthetic procedure effective for upper teeth and soft tissue; placement of anesthetic under the gum, allowing it to seep into bone.

Eosinophils
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.



SIMILAR TERMS
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Eosin
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosin (yellowish) (free acid)
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosin Y
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosine
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosine B
A red fluorescein dye used as a histologic stain. It may be cytotoxic, mutagenic, and inhibit certain mitochondrial functions.

Eosine Bluish
A red fluorescein dye used as a histologic stain. It may be cytotoxic, mutagenic, and inhibit certain mitochondrial functions.

Eosine I Bluish
A red fluorescein dye used as a histologic stain. It may be cytotoxic, mutagenic, and inhibit certain mitochondrial functions.

Eosine I Bluish, Dipotassium Salt
A red fluorescein dye used as a histologic stain. It may be cytotoxic, mutagenic, and inhibit certain mitochondrial functions.

Eosine Yellowish
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosine Yellowish-(YS)
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosine Yellowish-(YS), Dipotassium Salt
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosine Yellowish-(YS), Potassium, Sodium Salt
A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.

Eosinophil
A polymorphonuclear leukocyte with large eosinophilic (i.e. red) cytoplasmic granules.

Eosinophil Adenoma
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)

Eosinophil Adenomas
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)

Eosinophil chemotactic factor of anaphylaxis (ECF-A)
A substrate released from mast cells during anaphylaxis which attracts eosinophils.

Eosinophil Chemotactic Factors
Cytotaxins liberated from normal or invading cells that specifically attract eosinophils; they may be complement fragments, lymphokines, neutrophil products, histamine or other; the best known is the tetrapeptide ECF-A, released mainly by mast cells.

Eosinophil Chemotaxins
Cytotaxins liberated from normal or invading cells that specifically attract eosinophils; they may be complement fragments, lymphokines, neutrophil products, histamine or other; the best known is the tetrapeptide ECF-A, released mainly by mast cells.

Eosinophil Differentiation Factor
Factor promoting eosinophil differentiation and activation in hematopoiesis. It also triggers activated B-cells for a terminal differentiation into Ig-secreting cells.

Eosinophil Mast Cell Growth Factor
A multilineage cell growth factor secreted by lymphocytes, epithelial cells, and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells. Also called multi-CSF, it is considered one of the hematopoietic colony stimulating factors.

Eosinophil-Mast Cell Growth-Factor
A multilineage cell growth factor secreted by lymphocytes, epithelial cells, and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells. Also called multi-CSF, it is considered one of the hematopoietic colony stimulating factors.

Eosinophilia
An abnormally high number of eosinophils in the blood. Normally, eosinophils constitute 1 to 3% of the peripheral blood leukocytes, at a count of 350 to 650 per cubic millimeter. Eosinophilia can be categorized as mild (less than 1500 eosinophils per cubic millimeter), moderate (1500 to 5000 per cubic millimeter), or severe (more than 5000 per cubic millimeter).

Eosinophilia Myalgia Syndrome
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Eosinophilia, Pulmonary
A disease characterized by pulmonary infiltrations of eosinophils and blood eosinophilia.

Eosinophilia, Tropical
A disease characterized by pulmonary infiltrations of eosinophils and blood eosinophilia.

Eosinophilia-myalgia syndrome
Resembles eosinophilic fasciitis - due to L-Tryptophan.

Eosinophilia-Myalgia Syndrome
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Eosinophilia-Myalgia Syndrome, L-Tryptophan-Related
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Eosinophilia-Myalgia Syndromes
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Eosinophilia-Myalgia Syndromes, L-Tryptophan-Related
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSPINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Eosinophilias
Abnormal increase in eosinophils in the blood, tissues or organs.

Eosinophilias, Pulmonary
A disease characterized by pulmonary infiltrations of eosinophils and blood eosinophilia.

Eosinophilias, Tropical
A disease characterized by pulmonary infiltrations of eosinophils and blood eosinophilia.

Eosinophilic Adenoma
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)

Eosinophilic Adenomas
A benign tumor, usually found in the anterior lobe of the pituitary gland, whose cells stain with acid dyes. Such pituitary tumors may give rise to excessive secretion of growth hormone, resulting in gigantism or acromegaly. A specific type of acidophil adenoma may give rise to nonpuerperal galactorrhea. (Dorland, 27th ed)

Eosinophilic gastroenteritis
Infection and swelling of the lining of the stomach, small intestine, or large intestine. The infection is caused by white blood cells (eosinophils).

Eosinophilic granuloma
A form of Histiocytosis-X. A rare cause of back pain in adolescence which may cause vertebral collapse.

Eosinophilic Granuloma
The most benign clinical form of Langerhans-cell histiocytosis (HISTIOCYTOSIS, LANGERHANS-CELL), which involves localized nodular lesions of the gastric mucosa, small intestine, bones, lungs, or skin, with infiltration by eosinophils. The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell.

Eosinophilic Granulomas
The most benign clinical form of Langerhans-cell histiocytosis (HISTIOCYTOSIS, LANGERHANS-CELL), which involves localized nodular lesions of the gastric mucosa, small intestine, bones, lungs, or skin, with infiltration by eosinophils. The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell.

Eosinophilic Leukemia
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. It is often referred to as idiopathic.

Eosinophilic Leukemias
A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs. It is often referred to as idiopathic.

Eosinophilic meningitis
Meningitis with a high percentage of eosinophils (a type of white blood cell) in the cerebrospinal fluid (CSF). The usual cause is the parasite Angiostrongylus cantonensis, also known as the rat lungworm. People become infected with this parasite by ingesting its larvae in raw or insufficiently cooked snails, slugs, freshwater prawns, frogs, or fish. Infection may also occur by consumption of fresh produce such as contaminated lettuce. When the larvae are ingested, they penetrate the intestinal tract, go into blood vessels, and eventually reach the meninges (the covering of the brain and spinal cord). The larvae usually die there shortly thereafter. An eosinophilic reaction develops in response to the dying larvae. It is manifested by an outpouring of eosinophils in the CSF.

Eosinophilic Pneumonia
A disease characterized by pulmonary infiltrations of eosinophils and blood eosinophilia.

Eosinophilic Pneumonias
A disease characterized by pulmonary infiltrations of eosinophils and blood eosinophilia.

Eosinophils
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.



PREVIOUS AND NEXT TERMS
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EMG
Electromyogram - recording and study of electrical activity in muscle.

Enthesis
Site of attachment of ligament or tendon to bone.

Enthesitis
Inflammation of an enthesis.

Enthesopathy
Abnormality of an enthesis (e.g. enthesitis - usually involving pain).

Eosinophilia-myalgia syndrome
Resembles eosinophilic fasciitis - due to L-Tryptophan.

Eosinophilic fasciitis

Eosinophilic granuloma
A form of Histiocytosis-X. A rare cause of back pain in adolescence which may cause vertebral collapse.

Epicondylitis
Enthesopathy at humeral epicondyle. May be medial (golfer's elbow) or lateral (tennis elbow).

Epiphyseal dysplasia
Developmental skeletal disorder. There are several types.

Erythema chronicum migrans
Spreading annular rash which appears at the site of tick-bite in Lyme disease.

Erythema marginatum
Rash occurring in rheumatic fever.

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