Duplication
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  Duplication



Duplication

   Part of a chromosome in duplicate, a particular kind of mutation (change) involving the production of one or more copies of any piece of DNA, including a gene or even an entire chromosome.

RELATED TERMS
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Chromosome
A structural unit within a eukaryotic nucleus that carries genes. A chromosome consists of a long, continuous strand of DNA and associated proteins.

Mutation
A change in DNA that alters a gene and thus the gene's product, leading in some cases to deformity or disease. Mutations can occur spontaneously during cell division or can be triggered by environmental stresses, such as sunlight, radiation, and chemicals.

DNA
Deoxyribo-Nucleic acid. DNA molecules carry the genetic information necessary for the organization and functioning of most living cells and control the inheritance of characteristics.

Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.



SIMILAR TERMS
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Duplex Doppler Ultrasonography
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.

Duplex Ultrasonography, Doppler
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.

Duplicate Gene
Two identical genes showing the same phenotypic action but localized in different regions of a chromosome or on different chromosomes. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Duplicate Genes
Two identical genes showing the same phenotypic action but localized in different regions of a chromosome or on different chromosomes. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Duplicate Publication (PT)
The designation given an article or book of identical or nearly identical material published simultaneously or successively with the material previously published elsewhere, without acknowledgment.

Duplicate Publication [Publication Type]
The designation given an article or book of identical or nearly identical material published simultaneously or successively with the material previously published elsewhere, without acknowledgment.

Duplicating Process
Reproduction of data in a new location or other destination, leaving the source data unchanged, although the physical form of the result may differ from that of the source.

Duplicating Processes
Reproduction of data in a new location or other destination, leaving the source data unchanged, although the physical form of the result may differ from that of the source.

Duplication, Gene
A chromosomal structural change resulting in the doubling of a section of the genome of prokaryotes and eukaryotes. The size of the duplicated segment may vary considerably. Duplications may be interchromosomal, with the duplicate segment incorporated into another chromosome, or intrachromosomal, with the duplicate region present in the same chromosome. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Duplications, Gene
A chromosomal structural change resulting in the doubling of a section of the genome of prokaryotes and eukaryotes. The size of the duplicated segment may vary considerably. Duplications may be interchromosomal, with the duplicate segment incorporated into another chromosome, or intrachromosomal, with the duplicate region present in the same chromosome. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

Duplin General Hospital
Duplin General Hospital is a hospital in Kenansville, North Carolina (USA).



PREVIOUS AND NEXT TERMS
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Ductus arteriosus
A key arterial shunt (ductus) in fetal life. Before birth, blood pumped from the heart through the pulmonary artery toward the lungs is shunted into the aorta. This arterial shunt is a short vessel called the ductus arteriosus. When the shunt is open, it is said to be patent.

Ductus, patent
Failure for the ductus arteriosus, an arterial shunt in fetal life, to close on schedule. Before birth, blood pumped from the heart through the pulmonary artery toward the lungs is shunted into the aorta. This arterial shunt is a short vessel called the ductus arteriosus. When the shunt is open, it is said to be patent.

Dumdum fever
Also called kala-azar, a chronic, potentially fatal parasitic disease of the viscera (the internal organs) due to infection by an agent called Leishmania donovani.

Dummy
In science experiments, a substance without any active ingredient, a placebo.

Duodenal biliary drainage
A procedure used to diagnose gallstones when suspicion is high but other tests are negative. A thin tube is passed through a nostril down the throat, through the esophagus and stomach, into the duodenum. Once the tube is in place, a synthetic hormone related to cholecystokinin is injected IV. It causes the gallbladder to contract and squeeze out bile into the duodenum. The bile then is sucked up through the tube and examined for the presence of cholesterol and pigment particles under a microscope. A modification of duodenal biliary drainage involves collection of bile through an endoscope at the time of EGD (esophagogastroduodenoscopy) or ERCP (endoscopic retrograde cholangio-pancreatography).

Duplication

Dupuytren contracture
A localized formation of scar tissue in the palm of the hand. The scarring accumulates in a tissue called the fascia beneath the skin of the palm that normally covers the tendons that pull the fingers grip. As Dupuytren contracture progresses, more of the fascia becomes thickened and shortened. Dimpling and puckering of the skin over the area eventually occur.

Dura
The outermost, toughest, and most fibrous of the three membranes (meninges) covering the brain and the spinal cord. Dura is short for dura mater (from the Latin for hard mother). Also called the pachymeninx (singular) or pachymeniges (plural).

Durable power of attorney
This is a type of advance medical directive in which legal documents provide the power of attorney to another person in the case of an incapacitating medical condition.

Dural
Pertaining to the dura.

Dural sac
The membranous sac that encases the spinal cord within the bony structure of the vertebral column. Dural refers to the dura, the name of the membrane around the spinal cord (and brain, too).

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