Denaturation, Nucleic Acid
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  Denaturation, Nucleic Acid



Denaturation, Nucleic Acid

   Disorganization of secondary structures of nucleic acids through cleavage of hydrogen bonds and hydrophobic linkages. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.

RELATED TERMS
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Cleavage
The process of cell division in the very early embryo before it becomes a blastocyst.

Hydrogen
Hydrogen. The first chemical element in the periodic table. It has the atomic symbol H, atomic number 1, and atomic weight 1. It exists, under normal conditions, as a colorless, odorless, tasteless, diatomic gas. Hydrogen ions are PROTONS. Besides the common H1 isotope, hydrogen exists as the stable isotope DEUTERIUM and the unstable, radioactive isotope TRITIUM.



SIMILAR TERMS
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Denaturations, Nucleic Acid
Disorganization of secondary structures of nucleic acids through cleavage of hydrogen bonds and hydrophobic linkages. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.

Denavir
A cream used in the treatment of recurrent herpes labialis (cold sores).



PREVIOUS AND NEXT TERMS
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Dendritic Cells
Immunocompetent cells of the lymphoid and hemopoietic systems and skin. They are also called interdigitating, reticular, and veiled cells. They function morphologically and phenotypically by processing antigens or presenting them to T-cells, thereby stimulating cellular immunity.

Dendritic Cell, Follicular
Cells with extensive dendritic processes found in the B-cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the DENDRITIC CELLS associated with T-cells. Follicular dendritic cells have Fc receptors (RECEPTORS, FC) and C3b receptors (RECEPTORS, COMPLEMENT 3B), but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T-cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B-cells during an immune response. (From Herbert et al., Dictionary of Immunology, 4th ed)

Dendritic Cell
Immunocompetent cells of the lymphoid and hemopoietic systems and skin. They are also called interdigitating, reticular, and veiled cells. They function morphologically and phenotypically by processing antigens or presenting them to T-cells, thereby stimulating cellular immunity.

Dendrites
Extensions of the nerve cell body. They are short and branched and receive stimuli from other NEURONS.

Denaturations, Nucleic Acid
Disorganization of secondary structures of nucleic acids through cleavage of hydrogen bonds and hydrophobic linkages. Denatured DNA appears to be a single-stranded flexible structure. The effects of denaturation on RNA are similar though less pronounced and largely reversible.

Denaturation, Nucleic Acid

Demyelinative Myelitis
Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)

Dengue Virus
A species of the genus FLAVIVIRUS which causes an acute febrile and sometimes hemorrhagic disease in man. Dengue is mosquito-borne and four serotypes are known.

Dengue Shock Syndrome
A distinct and virulent form of DENGUE characterized by thrombocytopenia and hemoconcentration (grades I and II) and distinguished by a positive tourniquet test. When accompanied by circulatory failure and shock (grades III and IV), it is called dengue shock syndrome. (From Dorland, 28th ed)

Dengue Hemorrhagic Fever
A distinct and virulent form of DENGUE characterized by thrombocytopenia and hemoconcentration (grades I and II) and distinguished by a positive tourniquet test. When accompanied by circulatory failure and shock (grades III and IV), it is called dengue shock syndrome. (From Dorland, 28th ed)

Dengue Fever
An acute infectious, eruptive, febrile disease caused by four antigenically related but distinct serotypes of the DENGUE VIRUS. It is transmitted by the bite of infected Aedes mosquitoes, especially A. aegypti. Classical dengue (dengue fever) is self-limiting and characterized by fever, myalgia, headache, and rash. DENGUE HEMORRHAGIC FEVER is a more virulent form of dengue virus infection and a separate clinical entity. (From Dorland, 28th ed)

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