Demyelinating Autoimmune Disease, Peripheral
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  Demyelinating Autoimmune Disease, Peripheral



Demyelinating Autoimmune Disease, Peripheral

   Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.

RELATED TERMS
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Diseases
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Injury
Injury is damage or harm caused to the structure or function of the body caused by an outside agent or force, which may be physical or chemical.

Dysfunction
Difficult function or abnormal function.

Peripheral
At or near the surface of the body. Located away from the center structure.

Nerve
Tissue that conveys sensation, temperature, position information to the brain.

Affect
This word is used to described observable behavior that represents the expression of a subjectively experienced feeling state (emotion). Common examples of affect are sadness, fear, joy, and anger. The normal range of expressed affect varies considerably between different cultures and even within the same culture. Types of affect include: euthymic, irritable, constricted; blunted; flat; inappropriate, and labile.

Myelin
The lipid substance forming a sheath around the axons of certain nerve fibers.

Forms
A management function in which standards and guidelines are developed for the developing, maintaining, and handling of forms and records.

Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.

CHRONIC
Ongoing or recurring. Chronic medical conditions include diabetes, epilepsy, and chronic fatigue syndrome.

Inflammation
A reaction to an injury to the body - by infection, chemicals or physical agents. The symptoms can be - depending on the location of the injury- redness, swelling, heat and pain. The purpose of the inflammation is to dilute and destroy the agent causing the inflammation. To do this, the immune system starts a cascade of actions that causes active cells to gather at the affected location. It is these cells and fluids that cause the redness, swelling, heat and pain.



SIMILAR TERMS
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Demyelinating Autoimmune Diseases, Brain
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Autoimmune Diseases, Central Nervous System
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Autoimmune Diseases, Cerebral
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Autoimmune Diseases, CNS
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Autoimmune Diseases, Spinal Cord
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Autoimmune Disorders, CNS
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Central Nervous System Diseases, Hereditary
Inherited conditions characterized by a loss of myelin in the central nervous system.

Demyelinating Disease
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Demyelinating Disease, Autoimmune, CNS
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Disease, Peripheral Autoimmune
Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.

Demyelinating Diseases
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Demyelinating Diseases, Central Nervous System, Hereditary
Inherited conditions characterized by a loss of myelin in the central nervous system.

Demyelinating Disorder
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Demyelinating Disorders
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Demyelinating Polyradiculoneuropathy, Acute Inflammatory
An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)

Demyelination
A degenerative process that erodes away the myelin sheath that normally protects nerve fibers. Demyelination exposes these fibers and appears to cause problems in nerve impulse conduction that may affect many physical systems. Demyelinization is seen in a number of diseases, particularly multiple sclerosis. Diagnosis is by functional observation and by testing for myelin protein in the blood.

Demyelinations
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Demyelinative Myelitis
Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)



PREVIOUS AND NEXT TERMS
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Demineralization Technique, Bone
Removal of mineral constituents or salts from bone or bone tissue. Demineralization is used as a method of studying bone strength and bone chemistry.

Delta 5-Androstene-3 beta,17 beta-diol
An adrenal-derived estrogenic metabolite of DHEA. Evidence exist for its use as an endocrine regulator of immune response.

Dementias, Multiinfarct
Loss of higher cortical functions with retained awareness due to multiple cortical or subcortical CEREBRAL INFARCTION. Memory, judgement, attention span, and impulse control are often impaired, and may be accompanied by PSEUDOBULBAR PALSY, hemiparesis, reflex abnormalities, and other signs of localized neurologic dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p1060)

Dehydrogenase, Hydroxyprostaglandin
Catalyzes reversibly the oxidation of hydroxyl groups of prostaglandins.

Demyelinating Autoimmune Diseases, Brain
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Demyelinating Autoimmune Disease, Peripheral

Demography, Historical
Statistical interpretation and description of a population with reference to distribution, composition, or structure.

Demosterol
An intermediate in the synthesis of cholesterol.

Demography, Prehistoric
Statistical interpretation and description of a population with reference to distribution, composition, or structure.

Demography, Family
Size and composition of the family.

Demography
Statistical interpretation and description of a population with reference to distribution, composition, or structure.

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