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    Inflammation of a whole digit. Due to tenosynovitis and often periostitis as well as arthritis. Seen in seronegative arthritis (typically psoriatic arthritis) and sarcoidosis.


A reaction to an injury to the body - by infection, chemicals or physical agents. The symptoms can be - depending on the location of the injury- redness, swelling, heat and pain. The purpose of the inflammation is to dilute and destroy the agent causing the inflammation. To do this, the immune system starts a cascade of actions that causes active cells to gather at the affected location. It is these cells and fluids that cause the redness, swelling, heat and pain.

A finger or toe.

Inflammation involving the periosteum. May result in new bone formation.

Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Arthritis occurs in various forms, such as the arthritis associated with infections, osteoarthritis, or rheumatoid arthritis. Many forms of vasculitis can also be associated with arthritis.

Refers to arthritis and means that the patient does not have rheumatoid factor in the blood. A proportion of patients with rheumatoid arthritis are 'seronegative'.

A chronic, systemic, granulomatous disease of unknown origin which may involve almost any body organ or tissue and is characterized by the presence of noncaseating nodules in the covering of the internal/external surfaces of the body.


An imidazole antifungal agent that is used topically and by intravenous infusion.

An antitumor antibiotic derived from Streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

Dactyl, dactyl
Prefix or suffix denoting involvement of the digits (fingers or toes).

Swelling of the fingers or toes.

Dactylolysis Spontanea
Spontaneous autoamputation of the fourth or fifth toe.


Removable (partial or complete) set of artificial teeth.

The production of dentures dispensed directly by laboratory technicians

Space between teeth.

Health (dental) maintenance organization which specifies a health care (dental) provider a patient may see. Profitability depends on minimization of treatment.

Dysphoria is the lack of ability to feel enjoyment at any activity, an emotional state characterized by malaise, anxiety, depression or unease. The opposite of dysphoria would be euphoria.


A connective tissue disorder in which a rash and muscle inflammation are the predominant features.

Dual Energy X-ray Absorptiometry. A means of measuring bone density to detect osteoporosis.

Diaphyseal aclasis
A syndrome in which there are multiple enchondromata.

Diastrophic dwarfism
Short stature, cleft palate, thick pinnae and other features. Autosomal recessive inheritance.

Disc prolapse
Condition in which an intervertebral disc is damaged and some of it protrudes. May cause sciatica if it does so in the vicinity of a major nerve in the spine.

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