DISC-PCR
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  DISC-PCR



DISC-PCR

   A technique that labels specific sequences in whole chromosomes by in situ DNA chain elongation or PCR (polymerase chain reaction).

RELATED TERMS
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Chromosomes
Filaments of genetic material in every cell nucleus that are made up of genes and that transmit genetic information from one generation of cells to the next.



SIMILAR TERMS
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Disc
Shortened terminology for an intervertebral disc, a disk-shaped piece of specialized tissue that separates the bones of the spinal column.

Disc Displacement, Intervertebral
An intervertebral disk in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.

Disc Displacements, Intervertebral
An intervertebral disk in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.

Disc prolapse
Condition in which an intervertebral disc is damaged and some of it protrudes. May cause sciatica if it does so in the vicinity of a major nerve in the spine.

Disc, cervical
A disk shaped piece of specialized tissue that separates the vertebral bones of the spinal column in the neck.

Disc, Compact
Computer disks storing data with a maximum reduction of space and bandwidth. The compact size reduces cost of transmission and storage.

Disc, Herniated
An intervertebral disk in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.

Disc, optic
The circular area in the back of the inside of the eye where the optic nerve connects to the retina. Also called the optic nerve head.

Disc, slipped
Rupturing of the tissue that separates the vertebral bones of the spinal column.

Discase
Discase is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): chymopapain.

Discectomies
Excision, in part or whole, of an intervertebral disk. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.

Discectomies, Percutaneous
Percutaneous excision of a herniated or displaced intervertebral disk by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.

Discectomy
Excision, in part or whole, of an intervertebral disk. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.

Discectomy, Percutaneous
Percutaneous excision of a herniated or displaced intervertebral disk by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.

Discharge
1.The flow of fluid from part of the body, such as from the nose or vagina. 2. The passing of an action potential, such as through a nerve or muscle fiber. 3. The release of a patient from a course of care. The doctor may then dictate a discharge summary.

Discharge Planning
The administrative process of discharging the patient, live or dead, from hospitals or other health facilities.

Discharge Plannings
The administrative process of discharging the patient, live or dead, from hospitals or other health facilities.

Discharge, Patient
The administrative process of discharging the patient, live or dead, from hospitals or other health facilities.

Discharge, Vaginal
A common gynecologic disorder characterized by an abnormal, nonbloody discharge from the genital tract.

Discharges, Patient
The administrative process of discharging the patient, live or dead, from hospitals or other health facilities.

Discharges, Vaginal
A common gynecologic disorder characterized by an abnormal, nonbloody discharge from the genital tract.

Discipline
The limits a parent or caregiver sets on a child's behavior for purposes of safety or socialization.

Discipline, Employee
Regulations or conditions imposed on employees by management in order to correct or prevent behaviors which are counterproductive to the organization.

Discipline, Personnel
Regulations or conditions imposed on employees by management in order to correct or prevent behaviors which are counterproductive to the organization.

Disciplines, Employee
Regulations or conditions imposed on employees by management in order to correct or prevent behaviors which are counterproductive to the organization.

Disciplines, Personnel
Regulations or conditions imposed on employees by management in order to correct or prevent behaviors which are counterproductive to the organization.

Discitides
Inflammation of an intervertebral disk or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

Discitis
Inflammation of an intervertebral disk or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

Disclosure
Revealing of information, by oral or written communication.

Disclosure, Financial
Revealing of information, by oral or written communication.

Disclosure, Information
Revealing of information, by oral or written communication.

Disclosure, Self
A willingness to reveal information about oneself to others.

Disclosures, Financial
Revealing of information, by oral or written communication.

Disclosures, Self
A willingness to reveal information about oneself to others.

Discoid lupus erythematosus
A round, red, scaling rash on the nose, forehead, cheeks, scalp or other areas of the body. It may be associated with systemic lupus erythematosus.

Discoid Lupus Erythematosus
A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.

Discoloration, Tooth
Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)

Discolorations, Tooth
Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)

Discolyses
The dissolving of the nucleus pulposus of a displaced intervertebral disk, usually by the direct injection of a proteolytic enzyme, especially chymopapain, into the diseased disk.

Discolysis
The dissolving of the nucleus pulposus of a displaced intervertebral disk, usually by the direct injection of a proteolytic enzyme, especially chymopapain, into the diseased disk.

Disconnection syndrome
Term coined by Norman Geschwind to describe the interruption of information transferred from one brain region to another.

Discordance
1. The presence of any given condition such as HIV in only one member of a couple. 2. In genetics, the presence of a phenotype such as asthma in only one members of a twin pair. 3. In clinical care, lack of agreement between physician and patient.In all sense, disconcordance is as opposed to concordance.

Discordant
1. Showing discordance, lack of agreement. A couple may be discordant for a sexually transmitted infection, with one partner having it and the other not. 2. In transplantation genetics, between different species. A discordant xenograft is a transplant between members of very different species

Discordant couple
A pair of long-term sexual partners in which one has a sexually transmitted infection and the other does not. The CDC has guidelines for counseling discordant couples in which the woman is HIV-infected and her husband is HIV-uninfected.

Discounting the illuminant
Illumination of the visual world tens to be non-uniform, and fluctuates. in order for the visual system to create a consistent perception of color and lightness it must somehow discount fluctuation and gradient in the lighting source.

Discrete Subaortic Stenoses
An anatomic alteration in the mitral valve apparatus and interventricular septum leading to obstruction of left ventricular outflow. (from Eur J Cardiothorac Surg 1998;14(3):296-303)

Discrete Subaortic Stenosis
An anatomic alteration in the mitral valve apparatus and interventricular septum leading to obstruction of left ventricular outflow. (from Eur J Cardiothorac Surg 1998;14(3):296-303)

Discretionary Adjustment
A system wherein reimbursement rates are set, for a given period of time, prior to the circumstances giving rise to actual reimbursement claims.

Discretionary Adjustment Factor
A system wherein reimbursement rates are set, for a given period of time, prior to the circumstances giving rise to actual reimbursement claims.

Discretionary Adjustment Factors
A system wherein reimbursement rates are set, for a given period of time, prior to the circumstances giving rise to actual reimbursement claims.

Discretionary Adjustments
A system wherein reimbursement rates are set, for a given period of time, prior to the circumstances giving rise to actual reimbursement claims.

Discriminant Analyses
A statistical analytic technique used with discrete dependent variables, concerned with separating sets of observed values and allocating new values. It is sometimes used instead of regression analysis.

Discriminant Analysis
A statistical analytic technique used with discrete dependent variables, concerned with separating sets of observed values and allocating new values. It is sometimes used instead of regression analysis.

Discrimination
Differential response to different stimuli.

Discrimination (Psychology)
Differential response to different stimuli.

Discrimination Disorder, Somatosensory
Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.

Discrimination Disorders, Somatosensory
Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.

Discrimination Learning
Learning that is manifested in the ability to respond differentially to various stimuli.

Discrimination Learnings
Learning that is manifested in the ability to respond differentially to various stimuli.

Discrimination Test, Speech
Tests of the ability to hear and understand speech as determined by scoring the number of words in a word list repeated correctly.

Discrimination Tests, Speech
Tests of the ability to hear and understand speech as determined by scoring the number of words in a word list repeated correctly.

Discrimination, Pitch
The ability to differentiate tones.

Discrimination, Sex
A preconceived judgment made without adequate evidence and not easily alterable by presentation of contrary evidence.

Discrimination, Social
A preconceived judgment made without adequate evidence and not easily alterable by presentation of contrary evidence.

Discrimination, Speech
The process whereby an utterance is decoded into a representation in terms of linguistic units (sequences of phonetic segments which combine to form lexical and grammatical morphemes).

Discriminations (Psychology)
Differential response to different stimuli.

Discriminations, Pitch
The ability to differentiate tones.

Discriminatory Aphasia, Auditory
A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.

Discriminatory Aphasias, Auditory
A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.

Discs, Compact
Computer disks storing data with a maximum reduction of space and bandwidth. The compact size reduces cost of transmission and storage.

Discs, Herniated
An intervertebral disk in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.



PREVIOUS AND NEXT TERMS
--------------------------------------

Discharge Planning
The administrative process of discharging the patient, live or dead, from hospitals or other health facilities.

Discectomy, Percutaneous
Percutaneous excision of a herniated or displaced intervertebral disk by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.

Discectomy
Excision, in part or whole, of an intervertebral disk. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.

Discectomies, Percutaneous
Percutaneous excision of a herniated or displaced intervertebral disk by posterolateral approach, always remaining outside the spinal canal. Percutaneous nucleotomy was first described by Hijikata in Japan in 1975. In 1985 Onik introduced automated percutaneous nucleotomy which consists in percutaneous aspiration of the nucleus pulposus. It is carried out under local anesthesia, thus reducing the surgical insult and requiring brief hospitalization, often performed on an outpatient basis. It appears to be a well-tolerated alternative to surgical diskectomy and chymopapain nucleolysis.

Discectomies
Excision, in part or whole, of an intervertebral disk. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.

DISC-PCR

Disclosure, Self
A willingness to reveal information about oneself to others.

Disclosure, Financial
Revealing of information, by oral or written communication.

Disclosure, Information
Revealing of information, by oral or written communication.

Disclosure
Revealing of information, by oral or written communication.

Discitis
Inflammation of an intervertebral disk or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

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