Corticotropin Releasing-Hormone Receptors
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  Corticotropin Releasing-Hormone Receptors



Corticotropin Releasing-Hormone Receptors

   Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

RELATED TERMS
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Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.

Hormone
A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions.

Affinity
A measure of the binding constant of a single antigen combining site with a monovalent antigenic determinant.

Intracellular
Within cells.

Corticotropin
Corticotropin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin.

Receptors
Areas on the outer part of a cell that allow the cell to join or bind with insulin that is in the blood.

Anterior
The front, as opposed to the posterior. The anterior surface of the heart is toward the breast bone (the sternum).

Pituitary
The gland from which a number of hormones are released into the bloodstream. These hormones include growth hormone, ACTH, B-lipocortin (the precursor to B-endorphorin), FSH, LH, and TSH.

Central
In anatomy and medicine (as elsewhere), central is the opposite of "peripheral" which means away from the center.



SIMILAR TERMS
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Cort-dome
Cort-dome is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortalone
Cortalone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): prednisolone.

Cortan
Cortan is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): prednisone.

Cortancyl
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.

Cortef
Cortef is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortef acetate
Cortef acetate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone acetate.

Cortenema
Cortenema is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortex
The outer layer of the cerebrum, densely packed with nerve cells.

Cortex Decortication, Cerebral
Partial or total removal, ablation, or destruction of the cerebral cortex; may be chemical. It is not used with animals that do not possess a cortex, i.e., it is used only with mammals.

Cortex Decortications, Cerebral
Partial or total removal, ablation, or destruction of the cerebral cortex; may be chemical. It is not used with animals that do not possess a cortex, i.e., it is used only with mammals.

Cortex Disorder, Auditory
Disorders of hearing or auditory perception resulting from disease of the central auditory pathways or auditory association cortical areas. These include HEARING LOSS, CENTRAL; cortical deafness; and AUDITORY PERCEPTUAL DISORDERS. Above the level of the pons, bilateral lesions are usually required to produce auditory dysfunction.

Cortex Disorders, Auditory
Disorders of hearing or auditory perception resulting from disease of the central auditory pathways or auditory association cortical areas. These include HEARING LOSS, CENTRAL; cortical deafness; and AUDITORY PERCEPTUAL DISORDERS. Above the level of the pons, bilateral lesions are usually required to produce auditory dysfunction.

Cortex Effect, Adrenal
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids.

Cortex Effects, Adrenal
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids.

Cortex, adrenal
The outer portion of the adrenal gland located on top of each kidney. The adrenal cortex produces steroid hormones which regulate carbohydrate and fat metabolism and mineralocorticoid hormones which regulate salt and water balance in the body.

Cortex, Adrenal
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids.

Cortex, Auditory
Area of the temporal lobe concerned with hearing.

Cortex, Cerebellar
The superficial gray matter of the cerebellum. It consists of two main layers, the stratum moleculare and the stratum granulosum. (Dorland, 28th ed)

Cortex, Cerebral
The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri. It reaches its highest development in man and is responsible for intellectual faculties and higher mental functions.

Cortex, Crystalline Lens
The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. It contains lens fibers and amorphous, intercellular substance.

Cortex, Entorhinal
The cytoarchitecturally well-defined area of multilaminate cerebral cortex on the medial aspect of the parahippocampal gyrus, immediately caudal to the olfactory cortex of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the hippocampus, the so-called PERFORANT PATHWAY. (Stedman, 25th ed)

Cortex, Kidney
The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL.

Cortex, Motor
Area of the frontal lobe concerned with primary motor control. It lies anterior to the central sulcus.

Cortex, Olfactory
Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; olfactory tract, olfactory tubercle, anterior perforated substance, and olfactory cortex. The term rhinencephalon is restricted to structures in the CNS receiving fibers from the olfactory bulb.

Cortex, Prefrontal
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the mediodorsal nucleus of the thalamus. The prefrontal cortex receives afferent fibers from numerous structures of the diencephalon, mesencephalon, and limbic system as well as cortical afferents of visual, auditory, and somatic origin.

Cortex, Somatosensory
Area of the parietal lobe concerned with receiving general sensations. It lies posterior to the central sulcus.

Cortex, Striate
Area of the occipital lobe concerned with vision.

Cortex, Visual
Area of the occipital lobe concerned with vision.

Cortexolone
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.

Corti Organ
The organ that contains the special sensory receptors for hearing. It is composed of a series of epithelial structures placed upon the inner part of the basilar membrane.

Cortical
Having to do with the cortex, the outer portion of an organ.

Cortical Blindness
A person with cortical blindness will have normal eyes and normal optic nerves but, nevertheless, will not be able to see. The cause of the blindness is with the cortex or surface of the brain that contains 32 or more sites for visual information processing. More recently, the preferred term for such individuals is cortical visual impairment, because many people will not be totally blind but will exhibit unusual visual losses; for example, they may be blind to stationary objects but be able to see moving objects.

Cortical blindness
Blindness due to loss or injury to the visual cortex, that section of the cerebral cortex responsible for vision, as through a stroke or traumatic brain damage.

Cortical Congenital Hyperostoses
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Congenital Hyperostosis
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Contusion
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Cortical Contusions
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Cortical Deafness
Hearing loss due to disease of the central nervous system auditory pathways, which originate in the cochlear nuclei of the pons and then ascend bilaterally to reach the inferior colliculi of the midbrain, medial geniculate bodies of the thalamus, and then the auditory cortices located in the temporal lobes. Bilateral lesions of the auditory pathways are usually required to cause central hearing loss. Cortical deafness refers to loss of hearing due to bilateral auditory cortex lesions. Unilateral brain stem lesions involving the cochlear nuclei may result in unilateral hearing loss.

Cortical Diplopia
A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Cortical Diplopias
A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Cortical Hyperostoses, Congenital
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Hyperostoses, Infantile
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Hyperostosis, Congenital
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Hyperostosis, Infantile
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Lewy Body Disease
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)

Cortical magnification factor
Defined as millimeters of cortex per degree of visual angle.

Cortical Vigilance
Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.

Corticaltectal pathway
Pathway from the cortex to the superior colliculi.

Cortices, Cerebral
The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri. It reaches its highest development in man and is responsible for intellectual faculties and higher mental functions.

Cortices, Entorhinal
The cytoarchitecturally well-defined area of multilaminate cerebral cortex on the medial aspect of the parahippocampal gyrus, immediately caudal to the olfactory cortex of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the hippocampus, the so-called PERFORANT PATHWAY. (Stedman, 25th ed)

Corticobulbar Tract
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticobulbar Tracts
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticoid I Receptor
Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.

Corticoid I Receptors
Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.

Corticoid II Receptor
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

Corticoid II Receptors
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

Corticoid Type I Receptors
Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.

Corticoid Type II Receptors
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

Corticoids


Corticoliberin
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticospinal Tract
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticospinal Tracts
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticosteroid
Hormones produced by the adrenal gland which are important to almost every function of cells and organs. They are divided into two groups: glucocorticoids and mineralocorticoids. Glucocorticoids regulate protein, carbohydrate, and fat metabolism. Mineralocorticoids regulate electrolyte balances.

Corticosteroid allergy
A delayed allergic reaction to corticosteroid (drugs similar to cortisone). This occurs in 1-4% of people who use corticosteroids for asthma or other allergic diseases. A positive patch test to a corticosteroid means the patient cannot use that particular steroid. Although cross allergy between corticosteroids is common, such patients usually can tolerate another corticosteroid.

Corticosteroid drugs
Anti-inflammatory drugs that interfere with the immune system, suppress it and thereby dampen the inflammatory overreaction. They can be used to treat a number of allergic diseases - e.g. allergic rhinitis, eczema and rheumatoid arthritis. Corticosteroid drugs come as creams, inhalants, tablets and eye drops.

Corticosteroid hormones
Hormones produced by the adrenal glands.

Corticosteroid Receptor
Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.

Corticosteroid Receptors
Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.

Corticosteroids
Sometimes referred to just as 'steroids'. Hormones (which occur naturally) which have a variety of actions when given therapeutically. Usually administered for their anti-inflammatory effect. Their use is limited by unwanted side-effects which may sometimes be serious.

Corticostriatal Spinal Degeneration
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticostriatal-Spinal Degeneration
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticostriatal-Spinal Degenerations
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticotrophin
Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)

Corticotrophin (1-39)
Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)

Corticotropin
Corticotropin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin.

Corticotropin (1-24)-Peptide
A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN) activity.

Corticotropin (1-24)-Tetracosapeptide
A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN) activity.

Corticotropin (1-39)
Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)

Corticotropin beta Lipotropin Precursor
A precursor protein, MW 30,000, synthesized mainly in the anterior pituitary gland but also found in the hypothalamus, brain, and several peripheral tissues. It incorporates the amino acid sequences of ACTH and beta-lipotropin. These two hormones, in turn, contain the biologically active peptides MSH, corticotropin-like intermediate lobe peptide, alpha-lipotropin, endorphins, and methionine enkephalin.

Corticotropin Receptor
Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

Corticotropin Receptors
Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

Corticotropin Releasing Factor
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Factor 41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Factor Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Hormone 41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Hormone Receptor
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing-Factor Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing-Hormone Receptor
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin-beta-Lipotropin Precursor
A precursor protein, MW 30,000, synthesized mainly in the anterior pituitary gland but also found in the hypothalamus, brain, and several peripheral tissues. It incorporates the amino acid sequences of ACTH and beta-lipotropin. These two hormones, in turn, contain the biologically active peptides MSH, corticotropin-like intermediate lobe peptide, alpha-lipotropin, endorphins, and methionine enkephalin.

Corticotropin-Releasing Factor
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-Releasing Factor-41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-releasing hormone
A hormone made by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland. Corticotropin-releasing hormone is abbreviated and often referred to as CRH.

Corticotropin-Releasing Hormone
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-Releasing Hormone (CRH)
The hormone released from the hypothalamus. It interacts with the pituitary to produce ACTH. This hormone uses cyclic AMP for its second messenger.

Corticotropin-Releasing Hormone Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin-Releasing Hormone-41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticoviridae
A family of icosahedral, lipid-containing, non-enveloped bacteriophages containing one genus (Corticovirus).

Corticovirus
A family of icosahedral, lipid-containing, non-enveloped bacteriophages containing one genus (Corticovirus).

Cortifair
The main glucocorticoid secreted by the adrenal cortex. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Cortifoam
Cortifoam is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone acetate.

Cortinarius
An extensive order of basidiomycetous fungi whose fruiting bodies are commonly call mushrooms.

Cortis Organ
The organ that contains the special sensory receptors for hearing. It is composed of a series of epithelial structures placed upon the inner part of the basilar membrane.

Cortisol
The hormone released from the adrenal glands in response to stress or low blood glucose. Its primary mode of action in times of stress is to shut down eicosanoid synthesis. Its synthesis in the adrenal gland requires the second messenger, cyclic AMP.

Cortisone
An adrenocorticoid hormone, a naturally occurring hormone made by and secreted by the adrenal cortex, the outer part (the cortex) of the adrenal gland.

Cortisone acetate
Cortisone acetate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cortisone acetate.

Cortisone Reductase
An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.

Cortisporin
Cortisporin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): bacitracin zinc; hydrocortisone; neomycin sulfate; polymyxin b sulfate.

Cortodoxone
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.

Cortone
Cortone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cortisone acetate.

Cortosyn
A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN) activity.

Cortril
Cortril is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortrophin-zinc
Cortrophin-zinc is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin-zinc hydroxide.

Cortrosyn
Cortrosyn is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cosyntropin.



PREVIOUS AND NEXT TERMS
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Corticostriatal Spinal Degeneration
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticosteroid Receptors
Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.

Corticotropin-Releasing Factor-41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-Releasing Factor
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-beta-Lipotropin Precursor
A precursor protein, MW 30,000, synthesized mainly in the anterior pituitary gland but also found in the hypothalamus, brain, and several peripheral tissues. It incorporates the amino acid sequences of ACTH and beta-lipotropin. These two hormones, in turn, contain the biologically active peptides MSH, corticotropin-like intermediate lobe peptide, alpha-lipotropin, endorphins, and methionine enkephalin.

Corticotropin Releasing-Hormone Receptors

Corticotropin Releasing-Hormone Receptor
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing-Factor Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone Receptor
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

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   corticotropinreleasing-hormonereceptors / orticotropin releasing-hormone receptors / crticotropin releasing-hormone receptors / coticotropin releasing-hormone receptors / coricotropin releasing-hormone receptors / cortcotropin releasing-hormone receptors / cortiotropin releasing-hormone receptors / cortictropin releasing-hormone receptors / corticoropin releasing-hormone receptors / corticotopin releasing-hormone receptors / corticotrpin releasing-hormone receptors / corticotroin releasing-hormone receptors / corticotropn releasing-hormone receptors / corticotropi releasing-hormone receptors / corticotropinreleasing-hormone receptors / corticotropin eleasing-hormone receptors / corticotropin rleasing-hormone receptors / corticotropin reeasing-hormone receptors / corticotropin relasing-hormone receptors / corticotropin relesing-hormone receptors / corticotropin releaing-hormone receptors / corticotropin releasng-hormone receptors / corticotropin releasig-hormone receptors / corticotropin releasin-hormone receptors / corticotropin releasinghormone receptors / corticotropin releasing-ormone receptors / corticotropin releasing-hrmone receptors / corticotropin releasing-homone receptors / corticotropin releasing-horone receptors / corticotropin releasing-hormne receptors / corticotropin releasing-hormoe receptors / corticotropin releasing-hormon receptors / corticotropin releasing-hormonereceptors / corticotropin releasing-hormone eceptors / corticotropin releasing-hormone rceptors / corticotropin releasing-hormone reeptors / corticotropin releasing-hormone recptors / corticotropin releasing-hormone recetors / corticotropin releasing-hormone recepors / corticotropin releasing-hormone receptrs / corticotropin releasing-hormone receptos / corticotropin releasing-hormone receptor / ccorticotropin releasing-hormone receptors / coorticotropin releasing-hormone receptors / corrticotropin releasing-hormone receptors / cortticotropin releasing-hormone receptors / cortiicotropin releasing-hormone receptors / corticcotropin releasing-hormone receptors / corticootropin releasing-hormone receptors / corticottropin releasing-hormone receptors / corticotrropin releasing-hormone receptors / corticotroopin releasing-hormone receptors / corticotroppin releasing-hormone receptors / corticotropiin releasing-hormone receptors / corticotropinn releasing-hormone receptors / corticotropin releasing-hormone receptors / corticotropin rreleasing-hormone receptors / corticotropin reeleasing-hormone receptors / corticotropin relleasing-hormone receptors / corticotropin releeasing-hormone receptors / corticotropin releaasing-hormone receptors / corticotropin releassing-hormone receptors / corticotropin releasiing-hormone receptors / corticotropin releasinng-hormone receptors / corticotropin releasingg-hormone receptors / corticotropin releasing--hormone receptors / corticotropin releasing-hhormone receptors / corticotropin releasing-hoormone receptors / corticotropin releasing-horrmone receptors / corticotropin releasing-hormmone receptors / corticotropin releasing-hormoone receptors / corticotropin releasing-hormonne receptors / corticotropin releasing-hormonee receptors / corticotropin releasing-hormone receptors / corticotropin releasing-hormone rreceptors / corticotropin releasing-hormone reeceptors / corticotropin releasing-hormone recceptors / corticotropin releasing-hormone receeptors / corticotropin releasing-hormone recepptors / corticotropin releasing-hormone recepttors / corticotropin releasing-hormone receptoors / corticotropin releasing-hormone receptorrs / corticotropin releasing-hormone receptorss / xorticotropin releasing-hormone receptors / sorticotropin releasing-hormone receptors / dorticotropin releasing-hormone receptors / forticotropin releasing-hormone receptors / vorticotropin releasing-hormone receptors / orticotropin releasing-hormone receptors / c9rticotropin releasing-hormone receptors / c0rticotropin releasing-hormone receptors / cprticotropin releasing-hormone receptors / clrticotropin releasing-hormone receptors / ckrticotropin releasing-hormone receptors / cirticotropin releasing-hormone receptors / c8rticotropin releasing-hormone receptors / co4ticotropin releasing-hormone receptors / co5ticotropin releasing-hormone receptors / cotticotropin releasing-hormone receptors / cogticotropin releasing-hormone receptors / cofticotropin releasing-hormone receptors / codticotropin releasing-hormone receptors / coeticotropin releasing-hormone receptors / co3ticotropin releasing-hormone receptors / cor5icotropin releasing-hormone receptors / cor6icotropin releasing-hormone receptors / coryicotropin releasing-hormone receptors / corhicotropin releasing-hormone receptors / corgicotropin releasing-hormone receptors / corficotropin releasing-hormone receptors / corricotropin releasing-hormone receptors / cor4icotropin releasing-hormone receptors / cortcotropin releasing-hormone receptors / cortixotropin releasing-hormone receptors / cortisotropin releasing-hormone receptors / cortidotropin releasing-hormone receptors / cortifotropin releasing-hormone receptors / cortivotropin releasing-hormone receptors / corti otropin releasing-hormone receptors / cortic9tropin releasing-hormone receptors / cortic0tropin releasing-hormone receptors / corticptropin releasing-hormone receptors / corticltropin releasing-hormone receptors / corticktropin releasing-hormone receptors / corticitropin releasing-hormone receptors / cortic8tropin releasing-hormone receptors / cortico5ropin releasing-hormone receptors / cortico6ropin releasing-hormone receptors / corticoyropin releasing-hormone receptors / corticohropin releasing-hormone receptors / corticogropin releasing-hormone receptors / corticofropin releasing-hormone receptors / corticorropin releasing-hormone receptors / cortico4ropin releasing-hormone receptors / corticot4opin releasing-hormone receptors / corticot5opin releasing-hormone receptors / corticottopin releasing-hormone receptors / corticotgopin releasing-hormone receptors / corticotfopin releasing-hormone receptors / corticotdopin releasing-hormone receptors / corticoteopin releasing-hormone receptors / corticot3opin releasing-hormone receptors / corticotr9pin releasing-hormone receptors / corticotr0pin releasing-hormone receptors / corticotrppin releasing-hormone receptors / corticotrlpin releasing-hormone receptors / corticotrkpin releasing-hormone receptors / corticotripin releasing-hormone receptors / corticotr8pin releasing-hormone receptors / corticotro0in releasing-hormone receptors / corticotro-in releasing-hormone receptors / corticotro[in releasing-hormone receptors / corticotro;in releasing-hormone receptors / corticotrolin releasing-hormone receptors / corticotrooin releasing-hormone receptors / corticotro9in releasing-hormone receptors / corticotropn releasing-hormone receptors / corticotropib releasing-hormone receptors / corticotropih releasing-hormone receptors / corticotropij releasing-hormone receptors / corticotropim releasing-hormone receptors / corticotropi releasing-hormone receptors / corticotropin 4eleasing-hormone receptors / corticotropin 5eleasing-hormone receptors / corticotropin teleasing-hormone receptors / corticotropin geleasing-hormone receptors / corticotropin feleasing-hormone receptors / corticotropin deleasing-hormone receptors / corticotropin eeleasing-hormone receptors / corticotropin 3eleasing-hormone receptors / corticotropin r3leasing-hormone receptors / corticotropin r4leasing-hormone receptors / corticotropin rrleasing-hormone receptors / corticotropin rfleasing-hormone receptors / corticotropin rdleasing-hormone receptors / corticotropin rsleasing-hormone receptors / corticotropin rwleasing-hormone receptors / corticotropin reoeasing-hormone receptors / corticotropin repeasing-hormone receptors / corticotropin re;easing-hormone receptors / corticotropin re.easing-hormone receptors / corticotropin re,easing-hormone receptors / corticotropin rekeasing-hormone receptors / corticotropin reieasing-hormone receptors / corticotropin rel3asing-hormone receptors / corticotropin rel4asing-hormone receptors / corticotropin relrasing-hormone receptors / corticotropin relfasing-hormone receptors / corticotropin reldasing-hormone receptors / corticotropin relsasing-hormone receptors / corticotropin relwasing-hormone receptors / corticotropin releqsing-hormone receptors / corticotropin relewsing-hormone receptors / corticotropin relessing-hormone receptors / corticotropin relexsing-hormone receptors / corticotropin relezsing-hormone receptors / corticotropin releawing-hormone receptors / corticotropin releaeing-hormone receptors / corticotropin releading-hormone receptors / corticotropin releaxing-hormone receptors / corticotropin releazing-hormone receptors / corticotropin releaaing-hormone receptors / corticotropin releaqing-hormone receptors / corticotropin releasng-hormone receptors / corticotropin releasibg-hormone receptors / corticotropin releasihg-hormone receptors / corticotropin releasijg-hormone receptors / corticotropin releasimg-hormone receptors / corticotropin releasi g-hormone receptors / corticotropin releasint-hormone receptors / corticotropin releasing=hormone receptors / corticotropin releasing[hormone receptors / corticotropin releasingphormone receptors / corticotropin releasing0hormone receptors / corticotropin releasing-yormone receptors / corticotropin releasing-uormone receptors / corticotropin releasing-jormone receptors / corticotropin releasing-normone receptors / corticotropin releasing-bormone receptors / corticotropin releasing-gormone receptors / corticotropin releasing-tormone receptors / corticotropin releasing-h9rmone receptors / corticotropin releasing-h0rmone receptors / corticotropin releasing-hprmone receptors / corticotropin releasing-hlrmone receptors / corticotropin releasing-hkrmone receptors / corticotropin releasing-hirmone receptors / corticotropin releasing-h8rmone receptors / corticotropin releasing-ho4mone receptors / corticotropin releasing-ho5mone receptors / corticotropin releasing-hotmone receptors / corticotropin releasing-hogmone receptors / corticotropin releasing-hofmone receptors / corticotropin releasing-hodmone receptors / corticotropin releasing-hoemone receptors / corticotropin releasing-ho3mone receptors / corticotropin releasing-hornone receptors / corticotropin releasing-horjone receptors / corticotropin releasing-horkone receptors / corticotropin releasing-hor,one receptors / corticotropin releasing-hor one receptors / corticotropin releasing-horm9ne receptors / corticotropin releasing-horm0ne receptors / corticotropin releasing-hormpne receptors / corticotropin releasing-hormlne receptors / corticotropin releasing-hormkne receptors / corticotropin releasing-hormine receptors / corticotropin releasing-horm8ne receptors / corticotropin releasing-hormobe receptors / corticotropin releasing-hormohe receptors / corticotropin releasing-hormoje receptors / corticotropin releasing-hormome receptors / corticotropin releasing-hormo e receptors / corticotropin releasing-hormon3 receptors / corticotropin releasing-hormon4 receptors / corticotropin releasing-hormonr receptors / corticotropin releasing-hormonf receptors / corticotropin releasing-hormond receptors / corticotropin releasing-hormons receptors / corticotropin releasing-hormonw receptors / corticotropin releasing-hormone 4eceptors / corticotropin releasing-hormone 5eceptors / corticotropin releasing-hormone teceptors / corticotropin releasing-hormone geceptors / corticotropin releasing-hormone feceptors / corticotropin releasing-hormone deceptors / corticotropin releasing-hormone eeceptors / corticotropin releasing-hormone 3eceptors / corticotropin releasing-hormone r3ceptors / corticotropin releasing-hormone r4ceptors / corticotropin releasing-hormone rrceptors / corticotropin releasing-hormone rfceptors / corticotropin releasing-hormone rdceptors / corticotropin releasing-hormone rsceptors / corticotropin releasing-hormone rwceptors / corticotropin releasing-hormone rexeptors / corticotropin releasing-hormone reseptors / corticotropin releasing-hormone redeptors / corticotropin releasing-hormone refeptors / corticotropin releasing-hormone reveptors / corticotropin releasing-hormone re eptors / corticotropin releasing-hormone rec3ptors / corticotropin releasing-hormone rec4ptors / corticotropin releasing-hormone recrptors / corticotropin releasing-hormone recfptors / corticotropin releasing-hormone recdptors / corticotropin releasing-hormone recsptors / corticotropin releasing-hormone recwptors / corticotropin releasing-hormone rece0tors / corticotropin releasing-hormone rece-tors / corticotropin releasing-hormone rece[tors / corticotropin releasing-hormone rece;tors / corticotropin releasing-hormone receltors / corticotropin releasing-hormone receotors / corticotropin releasing-hormone rece9tors / corticotropin releasing-hormone recep5ors / corticotropin releasing-hormone recep6ors / corticotropin releasing-hormone recepyors / corticotropin releasing-hormone recephors / corticotropin releasing-hormone recepgors / corticotropin releasing-hormone recepfors / corticotropin releasing-hormone receprors / corticotropin releasing-hormone recep4ors / corticotropin releasing-hormone recept9rs / corticotropin releasing-hormone recept0rs / corticotropin releasing-hormone receptprs / corticotropin releasing-hormone receptlrs / corticotropin releasing-hormone receptkrs / corticotropin releasing-hormone receptirs / corticotropin releasing-hormone recept8rs / corticotropin releasing-hormone recepto4s / corticotropin releasing-hormone recepto5s / corticotropin releasing-hormone receptots / corticotropin releasing-hormone receptogs / corticotropin releasing-hormone receptofs / corticotropin releasing-hormone receptods / corticotropin releasing-hormone receptoes / corticotropin releasing-hormone recepto3s / corticotropin releasing-hormone receptorw / corticotropin releasing-hormone receptore / corticotropin releasing-hormone receptord / corticotropin releasing-hormone receptorx / corticotropin releasing-hormone receptorz / corticotropin releasing-hormone receptora / corticotropin releasing-hormone receptorq /