Corticosteroid drugs
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  Corticosteroid drugs



Corticosteroid drugs

    Anti-inflammatory drugs that interfere with the immune system, suppress it and thereby dampen the inflammatory overreaction. They can be used to treat a number of allergic diseases - e.g. allergic rhinitis, eczema and rheumatoid arthritis. Corticosteroid drugs come as creams, inhalants, tablets and eye drops.

RELATED TERMS
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Drugs
Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.

Immune
Resistant to a particular disease.

Diseases
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Rhinitis
An inflammation of the mucous membrane that lines the nose, often due to allergy to pollen, dust or other airborne substances, which causes sneezing, itching, a runny nose and nasal congestion.

Eczema
A disorder of the skin like psoriasis and also considered to be related to malfunctions of the immune system. Symptoms include red, itchy skin and sores that ooze and crust over. One out of ten children develops eczema, but more than half of them lose it by the time they reach their teens.

Arthritis
Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Arthritis occurs in various forms, such as the arthritis associated with infections, osteoarthritis, or rheumatoid arthritis. Many forms of vasculitis can also be associated with arthritis.

Corticosteroid
Hormones produced by the adrenal gland which are important to almost every function of cells and organs. They are divided into two groups: glucocorticoids and mineralocorticoids. Glucocorticoids regulate protein, carbohydrate, and fat metabolism. Mineralocorticoids regulate electrolyte balances.



SIMILAR TERMS
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Cort-dome
Cort-dome is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortalone
Cortalone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): prednisolone.

Cortan
Cortan is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): prednisone.

Cortancyl
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.

Cortef
Cortef is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortef acetate
Cortef acetate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone acetate.

Cortenema
Cortenema is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortex
The outer layer of the cerebrum, densely packed with nerve cells.

Cortex Decortication, Cerebral
Partial or total removal, ablation, or destruction of the cerebral cortex; may be chemical. It is not used with animals that do not possess a cortex, i.e., it is used only with mammals.

Cortex Decortications, Cerebral
Partial or total removal, ablation, or destruction of the cerebral cortex; may be chemical. It is not used with animals that do not possess a cortex, i.e., it is used only with mammals.

Cortex Disorder, Auditory
Disorders of hearing or auditory perception resulting from disease of the central auditory pathways or auditory association cortical areas. These include HEARING LOSS, CENTRAL; cortical deafness; and AUDITORY PERCEPTUAL DISORDERS. Above the level of the pons, bilateral lesions are usually required to produce auditory dysfunction.

Cortex Disorders, Auditory
Disorders of hearing or auditory perception resulting from disease of the central auditory pathways or auditory association cortical areas. These include HEARING LOSS, CENTRAL; cortical deafness; and AUDITORY PERCEPTUAL DISORDERS. Above the level of the pons, bilateral lesions are usually required to produce auditory dysfunction.

Cortex Effect, Adrenal
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids.

Cortex Effects, Adrenal
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids.

Cortex, adrenal
The outer portion of the adrenal gland located on top of each kidney. The adrenal cortex produces steroid hormones which regulate carbohydrate and fat metabolism and mineralocorticoid hormones which regulate salt and water balance in the body.

Cortex, Adrenal
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids.

Cortex, Auditory
Area of the temporal lobe concerned with hearing.

Cortex, Cerebellar
The superficial gray matter of the cerebellum. It consists of two main layers, the stratum moleculare and the stratum granulosum. (Dorland, 28th ed)

Cortex, Cerebral
The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri. It reaches its highest development in man and is responsible for intellectual faculties and higher mental functions.

Cortex, Crystalline Lens
The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. It contains lens fibers and amorphous, intercellular substance.

Cortex, Entorhinal
The cytoarchitecturally well-defined area of multilaminate cerebral cortex on the medial aspect of the parahippocampal gyrus, immediately caudal to the olfactory cortex of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the hippocampus, the so-called PERFORANT PATHWAY. (Stedman, 25th ed)

Cortex, Kidney
The outer zone of the KIDNEY, beneath the capsule, consisting of KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; and KIDNEY TUBULES, PROXIMAL.

Cortex, Motor
Area of the frontal lobe concerned with primary motor control. It lies anterior to the central sulcus.

Cortex, Olfactory
Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; olfactory tract, olfactory tubercle, anterior perforated substance, and olfactory cortex. The term rhinencephalon is restricted to structures in the CNS receiving fibers from the olfactory bulb.

Cortex, Prefrontal
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the mediodorsal nucleus of the thalamus. The prefrontal cortex receives afferent fibers from numerous structures of the diencephalon, mesencephalon, and limbic system as well as cortical afferents of visual, auditory, and somatic origin.

Cortex, Somatosensory
Area of the parietal lobe concerned with receiving general sensations. It lies posterior to the central sulcus.

Cortex, Striate
Area of the occipital lobe concerned with vision.

Cortex, Visual
Area of the occipital lobe concerned with vision.

Cortexolone
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.

Corti Organ
The organ that contains the special sensory receptors for hearing. It is composed of a series of epithelial structures placed upon the inner part of the basilar membrane.

Cortical
Having to do with the cortex, the outer portion of an organ.

Cortical Blindness
A person with cortical blindness will have normal eyes and normal optic nerves but, nevertheless, will not be able to see. The cause of the blindness is with the cortex or surface of the brain that contains 32 or more sites for visual information processing. More recently, the preferred term for such individuals is cortical visual impairment, because many people will not be totally blind but will exhibit unusual visual losses; for example, they may be blind to stationary objects but be able to see moving objects.

Cortical blindness
Blindness due to loss or injury to the visual cortex, that section of the cerebral cortex responsible for vision, as through a stroke or traumatic brain damage.

Cortical Congenital Hyperostoses
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Congenital Hyperostosis
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Contusion
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Cortical Contusions
Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Cortical Deafness
Hearing loss due to disease of the central nervous system auditory pathways, which originate in the cochlear nuclei of the pons and then ascend bilaterally to reach the inferior colliculi of the midbrain, medial geniculate bodies of the thalamus, and then the auditory cortices located in the temporal lobes. Bilateral lesions of the auditory pathways are usually required to cause central hearing loss. Cortical deafness refers to loss of hearing due to bilateral auditory cortex lesions. Unilateral brain stem lesions involving the cochlear nuclei may result in unilateral hearing loss.

Cortical Diplopia
A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Cortical Diplopias
A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.

Cortical Hyperostoses, Congenital
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Hyperostoses, Infantile
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Hyperostosis, Congenital
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Hyperostosis, Infantile
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)

Cortical Lewy Body Disease
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)

Cortical magnification factor
Defined as millimeters of cortex per degree of visual angle.

Cortical Vigilance
Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.

Corticaltectal pathway
Pathway from the cortex to the superior colliculi.

Cortices, Cerebral
The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon and folds into gyri. It reaches its highest development in man and is responsible for intellectual faculties and higher mental functions.

Cortices, Entorhinal
The cytoarchitecturally well-defined area of multilaminate cerebral cortex on the medial aspect of the parahippocampal gyrus, immediately caudal to the olfactory cortex of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the hippocampus, the so-called PERFORANT PATHWAY. (Stedman, 25th ed)

Corticobulbar Tract
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticobulbar Tracts
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticoid I Receptor
Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.

Corticoid I Receptors
Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.

Corticoid II Receptor
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

Corticoid II Receptors
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

Corticoid Type I Receptors
Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.

Corticoid Type II Receptors
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.

Corticoids


Corticoliberin
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticospinal Tract
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticospinal Tracts
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.

Corticosteroid
Hormones produced by the adrenal gland which are important to almost every function of cells and organs. They are divided into two groups: glucocorticoids and mineralocorticoids. Glucocorticoids regulate protein, carbohydrate, and fat metabolism. Mineralocorticoids regulate electrolyte balances.

Corticosteroid allergy
A delayed allergic reaction to corticosteroid (drugs similar to cortisone). This occurs in 1-4% of people who use corticosteroids for asthma or other allergic diseases. A positive patch test to a corticosteroid means the patient cannot use that particular steroid. Although cross allergy between corticosteroids is common, such patients usually can tolerate another corticosteroid.

Corticosteroid hormones
Hormones produced by the adrenal glands.

Corticosteroid Receptor
Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.

Corticosteroid Receptors
Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.

Corticosteroids
Sometimes referred to just as 'steroids'. Hormones (which occur naturally) which have a variety of actions when given therapeutically. Usually administered for their anti-inflammatory effect. Their use is limited by unwanted side-effects which may sometimes be serious.

Corticostriatal Spinal Degeneration
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticostriatal-Spinal Degeneration
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticostriatal-Spinal Degenerations
A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.

Corticotrophin
Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)

Corticotrophin (1-39)
Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)

Corticotropin
Corticotropin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin.

Corticotropin (1-24)-Peptide
A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN) activity.

Corticotropin (1-24)-Tetracosapeptide
A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN) activity.

Corticotropin (1-39)
Pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex. It is also present in human female urine and in the serum of pregnant mares. The substance is a single-chain polypeptide containing 39 amino acids, the first 24 of which are identical in all species. This 24-amino acid segment is said to be responsible for the biological activity of the peptide while the remaining 15-amino acid segment is said to be necessary for any immunological specificity. (From Merck Index, 11th ed)

Corticotropin beta Lipotropin Precursor
A precursor protein, MW 30,000, synthesized mainly in the anterior pituitary gland but also found in the hypothalamus, brain, and several peripheral tissues. It incorporates the amino acid sequences of ACTH and beta-lipotropin. These two hormones, in turn, contain the biologically active peptides MSH, corticotropin-like intermediate lobe peptide, alpha-lipotropin, endorphins, and methionine enkephalin.

Corticotropin Receptor
Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

Corticotropin Receptors
Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

Corticotropin Releasing Factor
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Factor 41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Factor Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Hormone 41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin Releasing Hormone Receptor
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing Hormone Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing-Factor Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing-Hormone Receptor
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin Releasing-Hormone Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin-beta-Lipotropin Precursor
A precursor protein, MW 30,000, synthesized mainly in the anterior pituitary gland but also found in the hypothalamus, brain, and several peripheral tissues. It incorporates the amino acid sequences of ACTH and beta-lipotropin. These two hormones, in turn, contain the biologically active peptides MSH, corticotropin-like intermediate lobe peptide, alpha-lipotropin, endorphins, and methionine enkephalin.

Corticotropin-Releasing Factor
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-Releasing Factor-41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-releasing hormone
A hormone made by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland. Corticotropin-releasing hormone is abbreviated and often referred to as CRH.

Corticotropin-Releasing Hormone
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticotropin-Releasing Hormone (CRH)
The hormone released from the hypothalamus. It interacts with the pituitary to produce ACTH. This hormone uses cyclic AMP for its second messenger.

Corticotropin-Releasing Hormone Receptors
Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Corticotropin-Releasing Hormone-41
A neuropeptide released by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland.

Corticoviridae
A family of icosahedral, lipid-containing, non-enveloped bacteriophages containing one genus (Corticovirus).

Corticovirus
A family of icosahedral, lipid-containing, non-enveloped bacteriophages containing one genus (Corticovirus).

Cortifair
The main glucocorticoid secreted by the adrenal cortex. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

Cortifoam
Cortifoam is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone acetate.

Cortinarius
An extensive order of basidiomycetous fungi whose fruiting bodies are commonly call mushrooms.

Cortis Organ
The organ that contains the special sensory receptors for hearing. It is composed of a series of epithelial structures placed upon the inner part of the basilar membrane.

Cortisol
The hormone released from the adrenal glands in response to stress or low blood glucose. Its primary mode of action in times of stress is to shut down eicosanoid synthesis. Its synthesis in the adrenal gland requires the second messenger, cyclic AMP.

Cortisone
An adrenocorticoid hormone, a naturally occurring hormone made by and secreted by the adrenal cortex, the outer part (the cortex) of the adrenal gland.

Cortisone acetate
Cortisone acetate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cortisone acetate.

Cortisone Reductase
An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.

Cortisporin
Cortisporin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): bacitracin zinc; hydrocortisone; neomycin sulfate; polymyxin b sulfate.

Cortodoxone
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.

Cortone
Cortone is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cortisone acetate.

Cortosyn
A synthetic polypeptide with adrenocorticotropic (CORTICOTROPIN) activity.

Cortril
Cortril is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrocortisone.

Cortrophin-zinc
Cortrophin-zinc is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): corticotropin-zinc hydroxide.

Cortrosyn
Cortrosyn is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cosyntropin.



PREVIOUS AND NEXT TERMS
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Cystourethrocele
Condition that results when the urethra and its supporting tissues weaken and drop into the vagina leading to stress incontinence.

Castration
The surgical removal of the testicles.

Causal treatment
A form of treatment which deals with the cause of a disease, not only the symptoms. Specific allergy vaccination is a causal treatment, the use of antihistamines is a symptomatic treatment.

Cell memory
If foreign substances (e.g. bacteria) enter the body, the immune system reacts by attacking and killing them. At the same time, T-cells and B-cells produce a population of memory cells. If you are subsequently exposed to the same bacteria, the immune system reacts much more quickly. In allergy, this mechanism is called "priming". You do not experience an allergic reaction the first time you are exposed to a particular allergen, but your body registers the allergen and, over time, you may develop an allergy to it.

Challenge test
See Provocation test

Corticosteroid drugs

Cell line
A general term applied to a defined population of cells that has been maintained in culture for an extended period and usually has undergone a spontaneous process, called transformation, that allows the cells to continue dividing (replicating) in culture indefinitely.

Comparative genomic hybridization (CGH)
A chromosomal screening technique that permits the detection of quantitative changes in chromosomal copy number without the need for cell culturing. It provides a global overview of chromosomal gains and losses throughout the whole genome (including extra, missing, and broken chromosomes), but cannot detect small changes in DNA sequence or changes in the imprinting state of a gene.

Chimera
An organism composed of cells derived from at least two genetically different individuals.

Chorion
The outermost of the two membranes surrounding the embryo/fetus, part of which forms the fetal portion of the placenta.

Cleavage
The process of cell division in the very early embryo before it becomes a blastocyst.

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   corticosteroiddrugs / orticosteroid drugs / crticosteroid drugs / coticosteroid drugs / coricosteroid drugs / cortcosteroid drugs / cortiosteroid drugs / corticsteroid drugs / corticoteroid drugs / corticoseroid drugs / corticostroid drugs / corticosteoid drugs / corticosterid drugs / corticosterod drugs / corticosteroi drugs / corticosteroiddrugs / corticosteroid rugs / corticosteroid dugs / corticosteroid drgs / corticosteroid drus / corticosteroid drug / ccorticosteroid drugs / coorticosteroid drugs / corrticosteroid drugs / cortticosteroid drugs / cortiicosteroid drugs / corticcosteroid drugs / corticoosteroid drugs / corticossteroid drugs / corticostteroid drugs / corticosteeroid drugs / corticosterroid drugs / corticosterooid drugs / corticosteroiid drugs / corticosteroidd drugs / corticosteroid drugs / corticosteroid ddrugs / corticosteroid drrugs / corticosteroid druugs / corticosteroid druggs / corticosteroid drugss / xorticosteroid drugs / sorticosteroid drugs / dorticosteroid drugs / forticosteroid drugs / vorticosteroid drugs / orticosteroid drugs / c9rticosteroid drugs / c0rticosteroid drugs / cprticosteroid drugs / clrticosteroid drugs / ckrticosteroid drugs / cirticosteroid drugs / c8rticosteroid drugs / co4ticosteroid drugs / co5ticosteroid drugs / cotticosteroid drugs / cogticosteroid drugs / cofticosteroid drugs / codticosteroid drugs / coeticosteroid drugs / co3ticosteroid drugs / cor5icosteroid drugs / cor6icosteroid drugs / coryicosteroid drugs / corhicosteroid drugs / corgicosteroid drugs / corficosteroid drugs / corricosteroid drugs / cor4icosteroid drugs / cortcosteroid drugs / cortixosteroid drugs / cortisosteroid drugs / cortidosteroid drugs / cortifosteroid drugs / cortivosteroid drugs / corti osteroid drugs / cortic9steroid drugs / cortic0steroid drugs / corticpsteroid drugs / corticlsteroid drugs / corticksteroid drugs / corticisteroid drugs / cortic8steroid drugs / corticowteroid drugs / corticoeteroid drugs / corticodteroid drugs / corticoxteroid drugs / corticozteroid drugs / corticoateroid drugs / corticoqteroid drugs / corticos5eroid drugs / corticos6eroid drugs / corticosyeroid drugs / corticosheroid drugs / corticosgeroid drugs / corticosferoid drugs / corticosreroid drugs / corticos4eroid drugs / corticost3roid drugs / corticost4roid drugs / corticostrroid drugs / corticostfroid drugs / corticostdroid drugs / corticostsroid drugs / corticostwroid drugs / corticoste4oid drugs / corticoste5oid drugs / corticostetoid drugs / corticostegoid drugs / corticostefoid drugs / corticostedoid drugs / corticosteeoid drugs / corticoste3oid drugs / corticoster9id drugs / corticoster0id drugs / corticosterpid drugs / corticosterlid drugs / corticosterkid drugs / corticosteriid drugs / corticoster8id drugs / corticosterod drugs / corticosteroie drugs / corticosteroir drugs / corticosteroif drugs / corticosteroiv drugs / corticosteroic drugs / corticosteroix drugs / corticosterois drugs / corticosteroiw drugs / corticosteroid erugs / corticosteroid rrugs / corticosteroid frugs / corticosteroid vrugs / corticosteroid crugs / corticosteroid xrugs / corticosteroid srugs / corticosteroid wrugs / corticosteroid d4ugs / corticosteroid d5ugs / corticosteroid dtugs / corticosteroid dgugs / corticosteroid dfugs / corticosteroid ddugs / corticosteroid deugs / corticosteroid d3ugs / corticosteroid dr7gs / corticosteroid dr8gs / corticosteroid drigs / corticosteroid drkgs / corticosteroid drjgs / corticosteroid drhgs / corticosteroid drygs / corticosteroid dr6gs / corticosteroid druts / corticosteroid drugw / corticosteroid druge / corticosteroid drugd / corticosteroid drugx / corticosteroid drugz / corticosteroid druga / corticosteroid drugq /