Albright syndrome
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  Albright syndrome



Albright syndrome

   A genetic disorder of bones, skin pigmentation and hormonal problems with premature sexual development. Also called McCune-Albright syndrome and polyostotic fibrous dysplasia.

RELATED TERMS
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Genetic
Hereditary. Having to do with the genes.

Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).

Premature
The term used to describe babies born before 37 weeks of gestation. Fewer than 10 percent of babies arrive this early.

Sexual
Pertaining to sex or, more particularly, the stimulation, responsiveness, and functions of the sex organs either alone or with one or more partners.

Development
The process of growth and differentiation.

Syndrome
A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection.

Dysplasia
An abnormality of growth.



SIMILAR TERMS
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PREVIOUS AND NEXT TERMS
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Alanine-glyoxylate aminotransferase
A liver enzyme known, for short, as AGXT. See: AGXT.

Alb-
"Prefix from the Latin ""albus"" meaning ""white."" As in albino and albinism. The term ""albino"" was first applied by the Portuguese to ""white"" people they encountered in West Africa. Those ""white"" people probably had partial or complete albinism, an inherited lack of pigment in the skin, hair, and eyes."

Albert Sabin
See: Sabin, Albert.

Albinism and hemorrhagic diathesis
See: Hermansky-Pudlak syndrome.

Albinism, oculocutaneous
An hereditary disorder characterized by deficiency of the pigment melanin in the eyes, skin and hair. The lack of eye pigment causes photophobia (sensitivity to light), nystagmus, and decreased visual acuity. Oculocutaneous albinism is conventionally classified as to whether it is tyrosinase-negative or tyrosinase-positive. In the tyrosinase-negative class, there is absence of the enzyme tyrosinase. In the tyrosinase-positive class, tyrosinase is present but it cannot enter pigment cells to do its job and make melanin.

Albright syndrome

Albuginea
Tough white fibrous tissue. The tunica albuginea of the testis, for example, is the layer of dense whitish inelastic tissue that surrounds the testis.

Albumen
"The white of an egg, the part of the egg from which meringues are made. Albus in Latin is white. Not to be confused with ""albumin"" which is the main protein in human blood and the key to the regulation of the osmotic pressure of blood."

Albuminuria
More than the normal amount of albumin in the urine. Albumin is the predominant protein in human blood and it is the key to the regulation of the osmotic pressure of blood. It is normal to have some albumin in urine. But too much albumin indicates that protein is leaking through the kidney. Albuminuria can mean many things. For example, albuminuria may be a sign of significant kidney disease or it may simply be a sequel of vigorous exercise. Albuminuria is a form of proteinuria.

ALCAM
A receptor expressed on T cells which is involved in the adhesion of cells. ALCAM stands for activated leukocyte cell adhesion molecule. The gene encoding ALCAM is on chromosome 3 in region 3q13.1-q13.2. The ALCAM gene has been reported to be less active in breast tumors with a poor prognosis.

Alcohol
An organic chemical in which one or more hydroxyl (OH) groups are attached to carbon (C) atoms in place of hydrogen (H) atoms. Common alcohols include ethyl alcohol or ethanol (found in alcoholic beverages), methyl alcohol or methanol (can cause blindness) and propyl alcohol or propanol (used as a solvent and antiseptic). Rubbing alcohol is a mixture of acetone, methyl isobutyl ketone, and ethyl alcohol. In everyday talk, alcohol usually refers to ethanol as, for example, in wine, beer, and liquor. It can cause changes in behavior and be addictive.

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