Albers-Schoenberg Disease
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  Albers-Schoenberg Disease

Albers-Schoenberg Disease

   Excessive formation of dense trabecular bone leading to pathological fractures, OSTEITIS, SPLENOMEGALY with infarct, ANEMIA, and extramedullary hemopoiesis (HEMATOPOIESIS, EXTRAMEDULLARY).


Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.

Breaks in bones or cartilage. (Stedman, 25th ed)

Enlargement of the spleen.

A localized area of ischemic necrosis produced by the occlusion of the blood vessels - either arterial supply or venous drainage.

Anemia is a condition in which a deficiency in the size or number of erythrocytes (red blood cells) or the amount of hemoglobin they contain limits the exchange of oxygen and carbon dioxide between the blood and the tissue cells. Most anemias are caused by a lack of nutrients required for normal erythrocyte synthesis, principally iron, vitamin B-12, and folic acid. Others result from a variety of conditions, such as hemorrhage, genetic abnormalities, chronic disease states or drug toxicity.


Albemarle Hospital
Albemarle Hospital is a hospital in Elizabeth City, North Carolina (USA).

Albendazole Monohydrochloride
A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

Albenza is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): albendazole .

Albert Einstein Healthcare
The Albert Einstein Healthcare is a hospital in Philadelphia, Pennsylvania, United States.

Albert Einstein HelathCare Network
Albert Einstein HelathCare Network is a hospital in Philadelphia, Pennsylvania (USA).

Albert Einstein Medical Center
The Albert Einstein Medical Center is a hospital in Philadelphia, Pennsylvania, United States.

Albert Sabin
See: Sabin, Albert.

Albert Schweitzer Hospital
The Albert Schweitzer Hospital is a hospital in Deschapelles, Haiti.

Alberta Children's Hospital
The Alberta Children's Hospital is a hospital in Calgary, Alberta, Canada.


Ala(2)-MePhe(4)-Gly-ol(5) Enkephalin
An enkephalin analog that selectively binds to the mu opioid receptor. It is used as a model for drug permeability experiments.

Alaryngeal Voice Productions
Methods of enabling a patient without a larynx or with a non-functional larynx to produce voice or speech. The methods may be pneumatic or electronic.

Alarm Systems, Equipment
Failure of equipment to perform up to standards. The failure may be due to defects or improper use.

Albinism, Yellow-Mutant
Heterogeneous group of autosomal recessive disorders comprising at least four recognized types, all having in common varying degrees of hypopigmentation of the skin, hair, and eyes. The two most common are the tyrosinase-positive and tyrosinase-negative types.

Albinism, Ocular
Albinism affecting the eye in which pigment of the hair and skin is normal or only slightly diluted. The classic type is X-linked (Nettleship-Falls), but an autosomal recessive form also exists. Ocular abnormalities may include reduced pigmentation of the iris, nystagmus, photophobia, strabismus, and decreased visual acuity.

Albers-Schoenberg Disease

Albendazole Monohydrochloride
A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed)

Alcaligenes eutropha
A gram-negative, facultatively chemoautotrophic bacterium, formerly called Alcaligenes eutrophus, found in water and soil.

Alcalase, Novo
A family of SERINE ENDOPEPTIDASES isolated from Bacillus subtilis. EC 3.4.21.-

Albuterol Sulfate
A racemic mixture with a 1:1 ratio of the r-isomer, levalbuterol, and s-albuterol. It is a short-acting beta2-adrenergic agonist with its main clinical use in ASTHMA.

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